NEK7 Protein (NEK7)

Catalog No. ABIN7939364

This Recombinant NEK7 protein is produced in Baculovirus infected Insect Cells.

Quick Overview for NEK7 Protein (NEK7) (ABIN7939364)

Target: NEK7

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: Functional Studies (Func), Activity Assay (AcA), Screening Assay (ScA)

Product Details

Purpose: Recombinant NEK7 protein

Application Details

Application Notes: All available data for a given product is shown on the lot-specific Technical Data Sheet

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Recombinant NEK7 protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handling Advice: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Storage: -80 °C

Storage Comment: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Target Details

Target: NEK7

Alternative Name: NEK7

Background:

Protein Background: NEK7 (NIMA Related Kinase 7) plays an important role in mitotic cell cycle progression and is required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. NEK7 Phosphorylates RPS6KB1 (By similarity) and phosphorylates EML4 at 'Ser-146' and promotes its dissociation from microtubules during mitosis which is required for efficient chromosome congression.

Short Description: Recombinant NEK7 protein was expressed in baculovirus expression system as the full length protein (accession number NP_598001.1) with a N-terminal FLAG tag. The molecular weight of the protein is 35.8 kDa.

Aliases: NIMA Related Kinase 7

Pathways: Inflammasome