SETD5 Protein (AA 185-416)

Catalog No. ABIN7939563

This Recombinant SETD5 protein is produced in Escherichia coli (E. coli).

Quick Overview for SETD5 Protein (AA 185-416) (ABIN7939563)

Target: SETD5 (SET Domain Containing 5 (SETD5))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Enzyme Kinetics (EK), Screening Assay (ScA)

Product Details

Protein Characteristics: AA 185-416

Purpose: Recombinant SETD5 (185-416) protein

Application Details

Application Notes: Recombinant SETD5 (185-416) protein is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Recombinant SETD5 (185-416) protein is supplied in 25 mM Tris-HCl pH 7.4, 500 mM NaCl, 10 % glycerol and 0.5 mM TCEP.

Handling Advice: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Storage: -80 °C

Storage Comment: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Target Details

Target: SETD5 (SET Domain Containing 5 (SETD5))

Alternative Name: SETD5

Background:

Protein Background: SETD5 (SET Domain Containing 5), based on sequence similarity, is a member of SET domain proteins, and might displays histone methyltransferase activity in vitro. It was reported to monomethylate 'Lys-9' of histone H3 in vitro. The physiological significance of this activity is unclear and its activity has yet to be determined. SETD5 is a probable transcriptional regulator that acts via the formation of large multiprotein complexes that modify and/or remodel the chromatin. According to researchers, it may act as a regulator of histone acetylation during gene transcription.

Short Description: Recombinant SETD5 (185-416) protein that includes amino acids 185-416 of human SETD5 protein (accession number NP_001073986.1) was expressed in E.coli and contains an N-terminal 6xHis tag. The molecular weight of this SETD5 protein is 30.4 kDa.

Aliases: SET Domain Containing 5, Histone-Lysine N-Methyltransferase SETD5, EC 2.1.1.43