STAT4 Protein
Quick Overview for STAT4 Protein (ABIN7939572)
Target
See all STAT4 ProteinsProtein Type
Origin
Source
Application
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Purpose
- Recombinant STAT4 protein
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Signal Transducer and Activator of Transcription 4 (STAT4) (AA 1-749) protein (His tag)
custom-made STAT4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Signal Transducer and Activator of Transcription 4 (STAT4) (AA 1-748) protein (His tag)custom-made STAT4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Signal Transducer and Activator of Transcription 4 (STAT4) (AA 1-748) protein (GST tag)STAT4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Signal Transducer and Activator of Transcription 4 (STAT4) protein (Myc-DYKDDDDK Tag)STAT4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Recombinant STAT4 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
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Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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Storage
- -80 °C
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Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
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Alternative Name
- STAT4
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Background
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Protein Background: STAT4 (Signal transducer and activator of transcription 4) is a member of the STAT family and localizes to the cytoplasm. STAT4 is phosphorylated after a variety of cytokines bind to the membrane and then dimerized STAT4 translocates to the nucleus to regulate gene expression. STAT4 play an essential role in a wide variety of cells and the pathogenesis of diverse human diseases, especially many kinds of autoimmune and inflammatory diseases, via activation by different cytokines through the Janus kinase (JAK)-STAT signaling pathway.
Short Description: Recombinant STAT4 protein was expressed in a baculovirus expression system as the full length protein (accession number NP_003142.1) with an N-terminal FLAG tag. The molecular weight of the protein is 87.21 kDa.
Aliases: SLEB11, DPMC
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Pathways
- JAK-STAT Signaling
Target
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