UBA7 Protein
Quick Overview for UBA7 Protein (ABIN7939725)
Target
See all UBA7 ProteinsProtein Type
Origin
Source
Application
-
-
Purpose
- Recombinant UBA7 (UBE1L) protein
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!ProductExpression SystemConjugateOriginPrice starts atExpression System HEK-293 CellsConjugate His tagOrigin HumanPrice starts at $12,595.45Expression System Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin HumanPrice starts at $19,692.86Your project requires further customization? Contact us and discover our custom protein solutions
-
Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) (AA 1-1012) protein (His tag)
custom-made UBA7 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) (AA 1-1012) protein (GST tag)UBA7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7) protein (Myc-DYKDDDDK Tag)UBA7 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Recombinant UBA7 (UBE1L) protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.
-
Handling Advice
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
-
Storage
- -80 °C
-
Storage Comment
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
-
-
- UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))
-
Alternative Name
- UBA7
-
Background
-
Protein Background: UBA7 is an E1-activating enzyme that catalyzes the covalent conjugation of the ubiquitin-like protein product of ISG15 to additional interferon stimulated proteins (ISGs) as well as other cellular proteins such as P53 in a process termed protein ISGylation. Plays an essential role in antiviral immunity together with ISG15 by restricting the replication of many viruses including rabies virus, influenza virus, sindbis virus, rotavirus or human cytomegalovirus. For example, ISG15 modification of influenza A protein NS1 disrupts the association of the NS1 with importin-alpha leading to NS1 nuclear import inhibition. ISGylation of human cytomegalovirs protein UL26 regulates its stability and inhibits its activities to suppress NF-kappa-B signaling.
Short Description: Recombinant UBA7 (UBE1L) protein was expressed in a baculovirus expression system as the full length protein (accession number NP_003326.2) with an N-terminal FLAG tag. The molecular weight of UBA7 is 112.96 kDa.
Aliases: UBE2, D8, UBA1B, UBE1L, Ubiquitin Like Modifier Activating Enzyme
Target
-
