UBA7 Protein (Myc-DYKDDDDK Tag)
-
- Target See all UBA7 Proteins
- UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))
- Protein Type
- Recombinant
- Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This UBA7 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human UBA7 / UBE1L protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product UBA7 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))
- Alternative Name
- Uba7,ube1l (UBA7 Products)
- Synonyms
- D8 Protein, UBA1B Protein, UBE1L Protein, UBE2 Protein, Ube1l Protein, 1300004C08Rik Protein, UBE1 Protein, xubc3 Protein, ubiquitin like modifier activating enzyme 7 Protein, ubiquitin-like modifier activating enzyme 7 Protein, ubiquitin conjugating enzyme E2 R2 S homeolog Protein, ubiquitin-like modifier-activating enzyme 7 Protein, UBA7 Protein, Uba7 Protein, ube2r2.S Protein, LOC100092397 Protein
- Background
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.
- Molecular Weight
- 111.5 kDa
- NCBI Accession
- NP_003326
-