HAVCR1 Protein (AA 22-212)
Quick Overview for HAVCR1 Protein (AA 22-212) (ABIN8056964)
Target
See all HAVCR1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 22-212
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Purpose
- Recombinant Mouse KIM-1 Protein(Halo Tag)
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Sequence
- Tyr22-Thr212
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1.0 EU/mg of the protein as determined by the LAL method
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Biological Activity Comment
- Not validated for activity
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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Buffer
- Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Expiry Date
- 12 months
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- HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
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Alternative Name
- KIM-1
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Background
- HAVCR1,TIM-1,T-cell immunoglobulin and mucin domain 1,TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hyperactivity (AHR), the hallmark of human asthma.
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Molecular Weight
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Calculated MW: 54 kDa
Observed MW: 60-65 kDa
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Gene ID
- 171283
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UniProt
- Q5QNS5
Target
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