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IL16 Protein

IL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % pure Active
Catalog No. ABIN934622
  • Target See all IL16 Proteins
    IL16 (Interleukin 16 (IL16))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 14
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Source
    • 24
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS
    Characteristics
    Purified recombinant Human IL16 protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to chemoattract human CD4+ T lymphoytes using a concentration range of 1.0-100.0 ng/mL.
    Purity
    > 97 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product IL16 Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    Lyophilized from 5 mM Na3PO4, pH 7.6.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Liu, Mills, Dixon, Vennarini, Cunningham, Del Vecchio, Das, Glass: "IL-16 signaling specifically induces STAT6 activation through CD4." in: Cytokine, Vol. 38, Issue 3, pp. 145-50, (2007) (PubMed).

  • Target
    IL16 (Interleukin 16 (IL16))
    Alternative Name
    IL16 (IL16 Products)
    Background
    IL16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL16 exists predominantly as a noncovalently linked multimer, but that some IL16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL16 also induces expression of IL2 receptor (IL2R) and MHC class II molecules on CD4 + T cells. Human and Mouse IL16 show significant cross-species reactivity.
    Alternative Names: IL-16 protein, IL16, IL-16 protein, Interleukin 16 protein, IL 16, Lymphocyte Chemoattractant Factor protein, IL 16 protein, LCF protein, IL-16
    Molecular Weight
    13.5 kDa
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