PLAT Protein

Catalog No. ABIN934797

This Native PLAT protein is expressed in Human.

Quick Overview for PLAT Protein (ABIN934797)

Target: PLAT (Plasminogen Activator, Tissue (PLAT))

Protein Type: Native

Origin: Human

Source: Human

Purity: > 95 % pure

Product Details

Characteristics: Purified Recombinant tPA protein (Human)
Protein Source: Prepared from human melanoma cell line

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 100 mM PBS, with 3.5 mg/mL L-arginine, and 0.001 % polysorbate Tween 80.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: PLAT (Plasminogen Activator, Tissue (PLAT))

Alternative Name: tPA

Background: Tissue plasminogen activator (abbreviated TPA or PLAT) is a protein involved in the breakdown of blood clots. It is a serine protease found on endothelial cells, the cells that line the blood vessels. As an enzyme, it catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown. Because it works on the clotting system, tPA is used in clinical medicine to treat only embolic or thrombotic stroke. Use is contraindicated in hemorrhagic stroke and head trauma.
Description: Prepared from human melanoma cell line.
Alternative Names: Tissue Plasminogen Activator protein, t-PA antibody

Pathways: Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome