Prothrombin Protein
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- Target See all Prothrombin (F2) Proteins
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
- Protein Type
- Native
- Biological Activity
- Active
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Origin
- Human
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Source
- Human
- Characteristics
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Purified native Human Prothrombin protein
Bioactivity: 9.7 units/mg protein - One unit of activity is equivalent to the Prothrombin activity in one milliliter of human normal plasma.
Protein Source: Human serum/plasma - Purity
- > 98 % pure
- Top Product
- Discover our top product F2 Protein
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Coagulation Factor II (thrombin) (F2) (AA 1-622) protein (GST tag)
F2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Coagulation Factor II (thrombin) (F2) (AA 263-362) protein (GST tag)F2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Coagulation Factor II (thrombin) (F2) (Active) protein (His tag)F2 Origin: Mouse Host: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as a liquid with 50 % Glycerol/H2 O (vol/vol).
- Precaution of Use
- Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Aliquot and store at -20 °C.
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- Target
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
- Alternative Name
- Prothrombin (F2 Products)
- Synonyms
- PT Protein, RPRGL2 Protein, THPH1 Protein, Cf-2 Protein, Cf2 Protein, FII Protein, thrombin Protein, zgc:66319 Protein, wu:fb57c10 Protein, wu:fd42e09 Protein, wu:fd59d01 Protein, prothrombin Protein, F2 Protein, coagulation factor II, thrombin Protein, coagulation factor II Protein, coagulation factor II (thrombin) Protein, F2 Protein, f2 Protein
- Background
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Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to gamma-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes.
Description: Human serum/plasma. - Molecular Weight
- 72 kDa
- Pathways
- Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
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