GADD45B Protein (AA 1-160)

Catalog No. ABIN935002

Recombinant GADD45B protein expressed in Escherichia coli (E. coli).

Quick Overview for GADD45B Protein (AA 1-160) (ABIN935002)

Target: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % pure

Product Details

Protein Characteristics: AA 1-160

Sequence: MTLEELVACD NAAQKMQTVT AAVEELLVAA QRQDRLTVGV YESAKLMNVD PDSVVLCLLA IDEEEEDDIA LQIHFTLIQS FCCDNDINIV RVSGMQRLAQ LLGEPAETQG TTEARDLHCL LVTNPHTDAW KSHGLVEVAS YCEESRGNNQ WVPYISLQER

Characteristics: Purified recombinant Human GADD45 B protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Application Details

Application Notes: GADD protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl, pH 7.5.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))

Alternative Name: GADD45B

Background: GADD45B is a member of GADD45 family (GADD45 alpha, beta, and gamma) that are nuclear proteins which interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45B is necessary for adult neurogenesis, including brain-derived neurotrophic factor and fibroblast growth factor. And therefore, this protein is implicated in affecting synaptic plasticity. Recombinant GADD45B protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: myeloid differentiation primary response gene protein, growth arrest and DNA-damage-inducible 45 beta protein, GADD45B protein, ADD45 beta protein, Growth arrest and DNA-damage-inducible beta protein, Growth arrest and DNA-damage-inducible protein protein, GADD45BETA protein, Negative growth-regulatory protein MyD118., MYD118 protein, beta GADD45 Beta protein, Myeloid differentiation primary response protein MyD118 protein, Growth arrest and DNA-damage-inducible protein

Molecular Weight: 17.8 kDa (160 AA)

Pathways: Cell Division Cycle