TBCA Protein (AA 1-108)

Catalog No. ABIN935042

This Recombinant TBCA protein is produced in Escherichia coli (E. coli).

Quick Overview for TBCA Protein (AA 1-108) (ABIN935042)

Target: TBCA (Tubulin Folding Cofactor A (TBCA))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 95 % pure

Product Details

Protein Characteristics: AA 1-108

Sequence: MADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA

Characteristics: Purified recombinant Human TBCA protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Application Details

Application Notes: TBCA protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 1 mM DTT, and 10 % glycerol.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: TBCA (Tubulin Folding Cofactor A (TBCA))

Alternative Name: TBCA

Background: Tubulin folding cofactor A, also known as TBCA, is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin in a quasi-native confirmation. This protein is essential for cell viability and its knockdown produces a decrease in the amount of soluble tubulin, modifications in microtubules and G1 cell cycle arrest. Recombinant human TBCA protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Tubulin cofactor a., Co chaperonin associated with a & b tubulin protein, Tubulin folding cofactor A protein, Cofactor A protein, chaperonin cofactor a protein, TCP1 chaperonin cofactor A protein, TBCA protein, tubulin specific chaperone a protein, Tubulin folding cofactor A CFA protein

Molecular Weight: 12.8 kDa (108 AA)

Pathways: SARS-CoV-2 Protein Interactome