DLL1 Protein
Quick Overview for DLL1 Protein (ABIN935315)
Target
See all DLL1 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- SGVFELKLQE FVNKKGLLGN RNCCRGGAGP PPCACRTFFR VCLKHYQASV SPEPPCTYGS AVTPVLGVDS FSLPDGGGAD SAFSNPIRFP FGFTWPGTFS LIIEALHTDS PDDLATENPE RLISRLATQR HLTVGEEWSQ DLHSSGRTDL KYSYRFVCDE HYYGEGCSVF CRPRDDAFGH FTCGERGEKV CNPGWKGPYC TEPICLPGCD EQHGFCDKPG ECKCRVGWQG RYCDECIRYP GCLHGTCQQP WQCNCQEGWG GLFCNQDLNY CTHHKPCKNG ATCTNTGQGS YTCSCRPGYT GATCELGIDE CDPSPCKNGG SCTDLENSYS CTCPPGFYGK ICELSAMTCA DGPCFNGGRC SDSPDGGYSC RCPVGYSGFN CEKKIDYCSS SPCSNGAKCV DLGDAYLCRC QAGFSGRHCD DNVDDCASSP CANGGTCRDG VNDFSCTCPP GYTGRNCSAP VSRCEHAPCH NGATCHERGH RYVCECARGY GGPNCQFLLP ELPPGPAVVD LTEKLEGQGG PF
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Characteristics
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Purified recombinant Human sDLL1 protein
Expression System: 293 cells
Bioactivity: Determined by the dose dependent growth suppression of the human acute mon °Cytic leukemia cell line, THP-1. sDLL-1 inhibits the proliferation in THP-1 cells using a concentration of 3.0-5.0 µg/mL. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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delta-Like 1 (DLL1) (AA 18-540) protein (His tag)
DLL1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 1 (DLL1) protein (Fc Tag)DLL1 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
delta-Like 1 (DLL1) (Active) protein (His tag)DLL1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
delta-Like 1 (DLL1) (AA 18-545) (Active) protein (Fc Tag)DLL1 Origin: Human Host: CHO Cells Recombinant >90 % (SDS-PAGE) SDS Active
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from PBS, pH 7.5,.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- DLL1 (delta-Like 1 (DLL1))
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Alternative Name
- sDLL1
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Background
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Human sDLL-1 comprises the extracellular signaling domain of DLL1, a member of a structurally-related family of single-pass type I trans-membrane proteins that serve as ligands for Notch receptors. It is expressed in the heart and pancreas, and to a lesser extent in various other tissues. DLL-1 functions to specifically activate the Notch-1 and Notch-2 receptors.
Alternative Names: sDLL-1 protein, Delta-like protein 1 protein, Delta-1 protein, sDLL1, sDLL 1 protein, sDLL 1, sDLL-1 protein, sDLL-1 -
Molecular Weight
- 57-60 kDa
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Pathways
- Notch Signaling, Stem Cell Maintenance
Target
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