IL-2 Protein
Quick Overview for IL-2 Protein (ABIN935487)
Target
See all IL-2 (IL2) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT
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Characteristics
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Purified recombinant Human IL2 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of Mouse CTLL-2 cells is ? 0.1 ng/mL, corresponding to a specific activity of ? 1 x 10^7 units/mg. -
Endotoxin Level
- < 0.1 ng per μg (1 EU/μg).
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Interleukin 2 (IL2) (AA 21-153) protein
IL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 2 (IL2) protein (His tag)IL2 Origin: Human Host: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Interleukin 2 (IL2) (AA 21-169) protein (His-Avi Tag)IL2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 2 (IL2) (AA 21-153) protein (mFc Tag)IL2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 2 (IL2) (AA 21-169) protein (His-Avi Tag,Biotin)IL2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 2 (IL2) (Active) proteinIL2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 2 (IL2) (AA 21-153) (Active) proteinIL2 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 2 (IL2) (Active) proteinIL2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Interleukin 2 (IL2) (AA 21-153) protein (His tag)IL2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 2 (IL2) (AA 21-153) (Active) protein (Fc Tag,AVI tag,Biotin)IL2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Comment
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Biological activity: The ED50 as determined by the dose-dependent stimulation of Mouse CTLL-2 cells is approx. 0.1 ng/mL, corresponding to a specific activity of approx. 1 x 10^7 units/mg.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with 100 mM CH3 COOH to a concentration of 0.1-1.3 g/mg.
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Buffer
- Supplied lyophilized with no additives.
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Preservative
- Without preservative
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- IL-2 (IL2) (Interleukin 2 (IL2))
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Alternative Name
- IL2
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Background
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IL2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL2/IL2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
Alternative Names: Interleukin-2 protein, Aldesleukin protein, Interleukin 2 protein, TCGF protein, IL 2 protein, IL2, T-cell growth factor protein, IL-2 protein, IL 2, IL 2 protein, IL-2 protein, IL-2 -
Molecular Weight
- 15.5 kDa
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Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
Target
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