IL-2 Protein
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- Target See all IL-2 (IL2) Proteins
- IL-2 (IL2) (Interleukin 2 (IL2))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFCQSII STLT
- Characteristics
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Purified recombinant Human IL2 protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of Mouse CTLL-2 cells is ? 0.1 ng/mL, corresponding to a specific activity of ? 1 x 10^7 units/mg. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product IL2 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Comment
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Biological activity: The ED50 as determined by the dose-dependent stimulation of Mouse CTLL-2 cells is approx. 0.1 ng/mL, corresponding to a specific activity of approx. 1 x 10^7 units/mg.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 mM CH3 COOH to a concentration of 0.1-1.3 g/mg.
- Buffer
- Supplied lyophilized with no additives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- IL-2 (IL2) (Interleukin 2 (IL2))
- Alternative Name
- IL2 (IL2 Products)
- Background
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IL2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL2/IL2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
Alternative Names: Interleukin-2 protein, Aldesleukin protein, Interleukin 2 protein, TCGF protein, IL 2 protein, IL2, T-cell growth factor protein, IL-2 protein, IL 2, IL 2 protein, IL-2 protein, IL-2 - Molecular Weight
- 15.5 kDa
- Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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