IL-22 Protein
Quick Overview for IL-22 Protein (ABIN935562)
Target
See all IL-22 (IL22) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI
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Characteristics
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Purified recombinant Human IL22 protein
Expression System: E.coli
Bioactivity: Determined by its ability to activate STAT following receptor ligand interaction. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Interleukin 22 (IL22) (AA 34-179) protein (His tag)
IL22 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 22 (IL22) (AA 34-179) protein (His tag)IL22 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 22 (IL22) (AA 34-179) protein (His-Avi Tag,Biotin)IL22 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Interleukin 22 (IL22) (AA 34-179) (Active) protein (His tag,AVI tag,Biotin)IL22 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 22 (IL22) protein (mFc Tag)IL22 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 22 (IL22) (AA 27-172) protein (His tag)IL22 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 22 (IL22) (AA 1-179) protein (GST tag)IL22 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 22 (IL22) (Active) proteinIL22 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE Active
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- IL-22 (IL22) (Interleukin 22 (IL22))
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Alternative Name
- IL22
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Background
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IL22 is a member of the IL10 family of regulatory cytokines which includes IL10, IL19, IL20, IL22, IL24 and IL26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL22 inhibits IL4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL22 signals through a receptor system consisting of IL10R-beta/CRF2-4 and IL22R, both of which are members of the class II cytokine-receptor family.
Alternative Names: IL 22 protein, Interleukin 22 protein, IL22, IL-22 protein, IL-22, IL-TIF protein, IL 22, IL-22 protein -
Molecular Weight
- 33.6 kDa
Target
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