IL-5 Protein
Quick Overview for IL-5 Protein (ABIN935590)
Target
See all IL-5 (IL5) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MEIPMSTVVK ETLIQLSTHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEILFQNL SLIKKYIDGQ KEKCGEERRK TRHFLDYLQE FLGVMSTEWA MEV
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Characteristics
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Purified recombinant Human IL5 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is 2 x 10^6 units/mg. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- IL-5 (IL5) (Interleukin 5 (IL5))
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Alternative Name
- IL5
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Background
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IL5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases.
Alternative Names: BCDFII protein, IL5, IL-5 protein, IL-5 protein, IL 5 protein, Interleukin 5 protein, TRF protein, EDF protein, IL 5, IL-5 -
Molecular Weight
- 26.0 kDa
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Pathways
- JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
Target
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