FGF7 Protein
Quick Overview for FGF7 Protein (ABIN935597)
Target
See all FGF7 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Sequence
- MCNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT
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Characteristics
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Purified recombinant Human KGF protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ? 10 ng/mL, corresponding to a specific activity of ? 1 x 10^5 units/mg. -
Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in PBS to a concentration of 0.5-1.0 mg/mL.
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Buffer
- Lyophilized from 15 mM Na3PO4 with 0.25 M NaCl, pH7.0.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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- FGF7 (Fibroblast Growth Factor 7 (FGF7))
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Alternative Name
- KGF
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Background
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Keratinocyte Growth Factor (KGF/FGF7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF7 plays a role in kidney and lung development, angiogenesis, and wound healing.
Alternative Names: Keratinocyte Growth Factor protein, HBGF-7 protein, Fibroblast Growth Factor-7 protein -
Molecular Weight
- 18.9 kDa
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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