TNFSF14 Protein
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- Target See all TNFSF14 Proteins
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Hi-5 Cells
- Sequence
- RLGEMVTRLP DGPAGSWEQL IQERRSHEVN PAAHLTGANS SLTGSGGPLL WETQLGLAFL RGLSYHDGAL VVTKAGYYYI YSKVQLGGVG CPLGLASTIT HGLYKRTPRY PEELELLVSQ QSPCGRATSS SRVWWDSSFL GGVVHLEAGE KVVVRVLDER LVRLRDGTRS YFGAFMV
- Characteristics
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Purified recombinant Human LIGHT protein
Expression System: Hi-5 cells - Purity
- > 95 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product TNFSF14 Protein
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Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (Trimer) protein (His-DYKDDDDK Tag)
TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) protein (His tag)TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) protein (Fc Tag)TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 89-240) protein (His-DYKDDDDK-Strep II Tag)TNFSF14 Origin: Human Host: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) (Active) protein (His tag)TNFSF14 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 71-240) protein (His-IF2DI Tag)TNFSF14 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-177) protein (GST tag)TNFSF14 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-204) protein (GST tag)TNFSF14 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 61-170) protein (GST tag)TNFSF14 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 59-240) protein (His tag)Crystallography grade TNFSF14 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Comment
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Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- Abstract
- TNFSF14 Products
- Synonyms
- TNFSF14 Protein, CD258 Protein, HVEML Protein, LIGHT Protein, LTg Protein, TR2 Protein, HVEM-L Protein, Ly113 Protein, TNF superfamily member 14 Protein, tumor necrosis factor (ligand) superfamily, member 14 Protein, TNFSF14 Protein, Tnfsf14 Protein
- Background
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LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF kb, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.
Alternative Names: CD258 protein, Ligand for herpesvirus entry mediator protein, TNF14 protein, TNFSF14 protein, HVEM-L protein - Molecular Weight
- 19.3 kDa
- Pathways
- Cancer Immune Checkpoints
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