NPX1 Protein

Catalog No. ABIN935691

This Recombinant NPX1 protein is expressed in Escherichia coli (E. coli).

Quick Overview for NPX1 Protein (ABIN935691)

Target: NPX1 (Neuronal Pentraxin 1 (NPX1))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 98 % pure

Product Details

Sequence: ACYCRIPACI AGERRYGYCI YQGRLWAFCC

Characteristics: Purified recombinant Human NP1 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract immature dendritic cells using a concentration of 1.0-10.0 ng/mL.

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: NPX1 (Neuronal Pentraxin 1 (NPX1))

Alternative Name: NP1

Background: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins which include NP-1, NP-2 and NP-3, are distinguished from the beta-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds.
Alternative Names: NP 1 protein, NP 1, Cryptdin protein, alpha Defensin-1 protein, Neutrophil Peptide-1 protein, HNP-1 protein, NP1, NP-1, NP-1 protein, NP-1 protein

Molecular Weight: 3.4 kDa

Pathways: Carbohydrate Homeostasis, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, SARS-CoV-2 Protein Interactome