NPX1 Protein (His tag)
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- Target See all NPX1 Proteins
- NPX1 (Neuronal Pentraxin 1 (NPX1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This NPX1 protein is labelled with His tag.
- Purpose
- Recombinant Human NPTX1 Protein (His Tag)
- Sequence
- Gln23-Asn432
- Characteristics
- Recombinant Human NPTX1 is produced by our Mammalian expression system and the target gene encoding Gln23-Asn432 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product NPX1 Protein
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Neuronal Pentraxin 1 (NPX1) (AA 141-240) protein (GST tag)
NPX1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Neuronal Pentraxin 1 (NPX1) (AA 23-432) protein (His tag)Crystallography grade NPX1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Neuronal Pentraxin 1 (NPX1) (AA 23-432) protein (His tag)Crystallography grade NPX1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Neuronal Pentraxin 1 (NPX1) protein (Myc-DYKDDDDK Tag)NPX1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS,1 mM EDTA,PH7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- NPX1 (Neuronal Pentraxin 1 (NPX1))
- Alternative Name
- NPTX1 (NPX1 Products)
- Synonyms
- NP1 Protein, D11Bwg1004e Protein, Np1 Protein, np1 Protein, nptx1 Protein, neuronal pentraxin 1 Protein, neuronal pentraxin 1 L homeolog Protein, Nptx1 Protein, NPTX1 Protein, nptx1 Protein, nptx1.L Protein
- Background
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Background: Neuronal Pentraxin (NPTX1, NP1) is a secreted glycoprotein within the Pentraxin family. NPTX1 is co-expressed and forms heteromultimers with the related secreted protein, NPTX2/NARP, NPTXR (Neuronal Pentraxin Receptor) at excitatory synapses. Mature human NPTX1 shares 97 % aa sequence identity with mouse, and rat NPTX1. It is produced by hippocampal, cerebral and cerebellar neurons, retinal ganglia and the inner nuclear layer of the retina. It is enriched on presynaptic axonal membranes where it forms complexes with NPTXR. It may be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
Synonym: Neuronal pentraxin-1,NPTX1,NP1
- Molecular Weight
- 45.9 kDa
- UniProt
- Q15818
- Pathways
- Carbohydrate Homeostasis, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, SARS-CoV-2 Protein Interactome
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