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PTPRB Products

(Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].

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Featured PTPRB Categories

PTPRB Antibodies

High quality antibodies with extensive validation data.

PTPRB ELISA Kits

Reliable ELISA kits for a wide range of species.

PTPRB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTPRB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7443743
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7439990
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7444100
Quantity 100 μL
Datasheet Datasheet

Recommended PTPRB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962129
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN511536
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method Quantitative
Validations
Cat. No. ABIN1057846
Quantity 96 tests
Datasheet Datasheet

Recommended PTPRB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7414459
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406167
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417285
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PTPRB products

Kim, Park, Kim, Noh, Park, Lie, Kim, Kim, Kwon: "SALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 9, pp. 9842-9857, (2020) (PubMed).

Winderlich, Keller, Cagna, Broermann, Kamenyeva, Kiefer, Deutsch, Nottebaum, Vestweber: "VE-PTP controls blood vessel development by balancing Tie-2 activity." in: The Journal of cell biology, Vol. 185, Issue 4, pp. 657-71, (2009) (PubMed).

Synonyms and alternative names related to PTPRB

protein tyrosine phosphatase, receptor type B (PTPRB), receptor-type tyrosine-protein phosphatase beta (LOC100380677), protein tyrosine phosphatase, receptor type, B (Ptprb), protein tyrosine phosphatase, receptor type B (Ptprb), 3230402H02Rik, C130094E24, HPTP-BETA, HPTPB, PTPB, PTPRB, Ptpz, R-PTP-BETA, Rptpb, VE-PTP, VEPTP, Veptp

Protein level used designations for PTPRB

  • protein tyrosine phosphatase, receptor type, B
  • Receptor-type tyrosine-protein phosphatase beta
  • receptor-type tyrosine-protein phosphatase beta-like
  • receptor-type tyrosine-protein phosphatase beta
  • VE-PTP
  • protein tyrosine phosphatase, receptor type, beta polypeptide
  • vascular endothelial protein tyrosine phosphatase
  • R-PTP-beta
  • protein-tyrosine phosphatase beta
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