PTPN22 Products
(Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))
Categories
This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009].
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Featured PTPN22 Categories
PTPN22 Antibodies
High quality antibodies with extensive validation data.
PTPN22 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PTPN22 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF, FACS
Validations
- (5)
Cat. No.
ABIN6391380
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN1513449
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
Cat. No.
ABIN565235
Quantity
100 μg
Datasheet
Datasheet
Recommended PTPN22 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971027
Quantity
96 tests
Datasheet
Datasheet
Recommended PTPN22 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1316837
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316839
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422139
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PTPN22 products
: "Measuring the specific activity of the protein tyrosine phosphatase Lyp." in: Journal of immunological methods, Vol. 388, Issue 1-2, pp. 33-9, (2013) (PubMed).: "High basal activity of the PTPN22 gain-of-function variant blunts leukocyte responsiveness negatively affecting IL-10 production in ANCA vasculitis." in: PLoS ONE, Vol. 7, Issue 8, pp. e42783, (2012) (PubMed).
Synonyms and alternative names related to PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (Ptpn22), protein tyrosine phosphatase, non-receptor type 22 (PTPN22), protein tyrosine phosphatase, non-receptor type 22 (Ptpn22), 70zpep, LYP, LYP1, LYP2, PEP, Ptpn8, PTPN8Protein level used designations for PTPN22
- PEST domain-enriched tyrosine phosphatase
- hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
- protein tyrosine phosphatase, non-receptor type 8
- tyrosine-protein phosphatase non-receptor type 22
- PEST-domain phosphatase
- lymphoid phosphatase
- lymphoid-specific protein tyrosine phosphatase
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