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PUM2 Products

(Pumilio Homolog 2 (Drosophila) (PUM2))

Categories

Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts (By similarity).

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Featured PUM2 Categories

PUM2 Antibodies

High quality antibodies with extensive validation data.

PUM2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PUM2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
Cat. No. ABIN392131
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN185369
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN391821
Quantity 400 μL
Datasheet Datasheet

Recommended PUM2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231949
Quantity 96 tests
Datasheet Datasheet

Recommended PUM2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316915
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094816
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136013
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PUM2 products

Valluy, Bicker, Aksoy-Aksel, Lackinger, Sumer, Fiore, Wüst, Seffer, Metge, Dieterich, Wöhr, Schwarting, Schratt: "A coding-independent function of an alternative Ube3a transcript during neuronal development." in: Nature neuroscience, Vol. 18, Issue 5, pp. 666-73, (2015) (PubMed).

Fiore, Rajman, Schwale, Bicker, Antoniou, Bruehl, Draguhn, Schratt: "MiR-134-dependent regulation of Pumilio-2 is necessary for homeostatic synaptic depression." in: The EMBO journal, Vol. 33, Issue 19, pp. 2231-46, (2014) (PubMed).

Friend, Brook, Bezirci, Sheets, Gray, Seli: "Embryonic poly(A)-binding protein (ePAB) phosphorylation is required for Xenopus oocyte maturation." in: The Biochemical journal, Vol. 445, Issue 1, pp. 93-100, (2012) (PubMed).

Marrero, Rossi, Darr, Tsoulfas, Rotundo: "Translational regulation of acetylcholinesterase by the RNA-binding protein Pumilio-2 at the neuromuscular synapse." in: The Journal of biological chemistry, Vol. 286, Issue 42, pp. 36492-9, (2011) (PubMed).

Christensen, Larsen, Kauppinen, Schratt: "Recombinant Adeno-Associated Virus-Mediated microRNA Delivery into the Postnatal Mouse Brain Reveals a Role for miR-134 in Dendritogenesis in Vivo." in: Frontiers in neural circuits, Vol. 3, pp. 16, (2010) (PubMed).

Kusz, Ginter-Matuszewska, Ziolkowska, Spik, Bierla, Jedrzejczak, Latos-Bielenska, Pawelczyk, Jaruzelska: "Polymorphisms of the human PUMILIO2 gene and male sterility." in: Molecular reproduction and development, Vol. 74, Issue 6, pp. 795-9, (2007) (PubMed).

Spik, Oczkowski, Olszak, Kotecki, Formanowicz, B?azewicz, Jaruzelska: "Candidate mRNAs interacting with fertility protein PUMILIO2 in the human germ line." in: Reproductive biology, Vol. 6 Suppl 1, pp. 37-42, (2006) (PubMed).

Padmanabhan, Richter: "Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation." in: Genes & development, Vol. 20, Issue 2, pp. 199-209, (2006) (PubMed).

Szakmary, Cox, Wang, Lin: "Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell self-renewal and differentiation." in: Current biology : CB, Vol. 15, Issue 2, pp. 171-8, (2005) (PubMed).

Masutomi, Possemato, Wong, Currier, Tothova, Manola, Ganesan, Lansdorp, Collins, Hahn: "The telomerase reverse transcriptase regulates chromatin state and DNA damage responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 23, pp. 8222-7, (2005) (PubMed).

Synonyms and alternative names related to PUM2

pumilio RNA binding family member 2 (pum2), pumilio RNA-binding family member 2 (Pum2), pumilio RNA binding family member 2 (PUM2), 5730503J23Rik, mKIAA0235, pum-2, PUMH2, PUML2, Pumm2

Protein level used designations for PUM2

  • pumilio-2
  • PUM1
  • pumilio homolog 2
  • pumilio 2
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