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PURA Products

(Purine-Rich Element Binding Protein A (PURA))

Categories

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008].

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Featured PURA Categories

PURA Antibodies

High quality antibodies with extensive validation data.

PURA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PURA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (6)
Cat. No. ABIN519543
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7444490
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN519546
Quantity 100 μg
Datasheet Datasheet

Recommended PURA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231950
Quantity 96 tests
Datasheet Datasheet

Recommended PURA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316919
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316917
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3086713
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PURA products

Moldovan, Moran: "The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition." in: PLoS genetics, Vol. 11, Issue 5, pp. e1005121, (2015) (PubMed).

Gazla, Carracedo: "Effect of intracellular Wolbachia on interspecific crosses between Drosophila melanogaster and Drosophila simulans." in: Genetics and molecular research : GMR, Vol. 8, Issue 3, pp. 861-9, (2009) (PubMed).

Kaminski, Darbinyan, Merabova, Deshmane, White, Khalili: "Protective role of Puralpha to cisplatin." in: Cancer biology & therapy, Vol. 7, Issue 12, pp. 1926-35, (2009) (PubMed).

Martins-de-Souza, Gattaz, Schmitt, Rewerts, Maccarrone, Dias-Neto, Turck: "Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia." in: European archives of psychiatry and clinical neuroscience, Vol. 259, Issue 3, pp. 151-63, (2009) (PubMed).

Darbinian, Cui, Basile, Del Valle, Otte, Miklossy, Sawaya, Amini, Khalili, Gordon: "Negative regulation of AbetaPP gene expression by pur-alpha." in: Journal of Alzheimer's disease : JAD, Vol. 15, Issue 1, pp. 71-82, (2008) (PubMed).

Wang, Johnson, Kinoshita, Babb, Buckley, Liebes, Melamed, Liu, Kurek, Ossowski, Ferrari: "Androgen receptor overexpression in prostate cancer linked to Pur alpha loss from a novel repressor complex." in: Cancer research, Vol. 68, Issue 8, pp. 2678-88, (2008) (PubMed).

Synonyms and alternative names related to PURA

purine-rich element binding protein A (pura), purine rich element binding protein A (Pura), purine rich element binding protein A (PURA), purine-rich element binding protein Aa (puraa), purine-rich element binding protein A L homeolog (pura.L), CAGER-1, Pur-alpha, PUR-ALPHA, pur-alpha, PUR1, pur1, PURALPHA, puralpha, ssCRE-BP, zgc:103411

Protein level used designations for PURA

  • purine-rich element binding protein A
  • Pur alpha
  • purine-rich single-stranded DNA-binding protein alpha
  • transcriptional activator protein Pur-alpha
  • pur-alpha
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