The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008].
BMP6
Origin: Human
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
AM, ADA, IA, ScA
BMP6
Origin: Mouse
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
AM, ADA, IA, ScA
Crews, Adame, Patrick, Delaney, Pham, Rockenstein, Hansen, Masliah: "Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 37, pp. 12252-62, (2010) (PubMed).
Jukes, Both, Leusink, Sterk, van Blitterswijk, de Boer: "Endochondral bone tissue engineering using embryonic stem cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6840-5, (2008) (PubMed).
Aliases for BMP6 Proteins
bone morphogenetic protein 6 (BMP6) Proteins bone morphogenetic protein 6 (bmp6) Proteins bone morphogenetic protein 6 S homeolog (bmp6.S) Proteins bone morphogenetic protein 6 (Bmp6) Proteins BMP6 Proteins D13Wsu115e Proteins vgr Proteins VGR Proteins vgr-1 Proteins vgr1 Proteins VGR1 Proteins Vgr1 Proteins zgc:113595 Proteins