Browse our anti-SHC3 (SHC3) Antibodies

Full name:: anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 3 Antibodies (SHC3)

On www.antibodies-online.com are 59 SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Antibodies from 16 different suppliers available. Additionally we are shipping SHC3 Proteins (6) and many more products for this protein. A total of 74 SHC3 products are currently listed.

Synonyms:: N-Shc, NSHC, Rai, ShcC

list all antibodies	Gene Name	GeneID	UniProt
	SHC3	53358	Q92529
	SHC3	114858
	SHC3	20418	Q61120
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Most Popular Reactivities for anti-SHC3 (SHC3) Antibodies

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anti-Human SHC3 Antibodies:

anti-Rat (Rattus) SHC3 Antibodies:

anti-Mouse (Murine) SHC3 Antibodies:

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Relevant Pathways for anti-SHC3 Antibodies

Neurotrophin Signaling Pathway

More product categories related to SHC3 Antibody

Top referenced anti-SHC3 Antibodies

Human Polyclonal SHC3 Primary Antibody for WB - ABIN2801960 : Liu, Meakin: ShcB and ShcC activation by the Trk family of receptor tyrosine kinases. in The Journal of biological chemistry 2002 (PubMed)
Show all 4 Pubmed References

More Antibodies against SHC3 Interaction Partners

Human SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) interaction partners

High SHC3 expression is associated with glioblastoma.
Rai (ShcC/N-Shc), a member of the family of Shc (show SHC1 Antibodies)-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells.
Polymorphism in RAI (show RNH1 Antibodies) and CD3EAP (show CD3EAP Antibodies) are associated with outcome of myeloma patients treated with high dose treatment.
amplification of SHC3 and EDG3 (show S1PR3 Antibodies) genes suggests that the two proteins co-operate and are important for ependymomas in vivo.
Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (show SHC1 Antibodies).
ALK-ShcC signal activation, possibly caused by co-amplification with the N-myc gene, might give additional effects on malignant tumor progression of neuroblastoma.ShcC is a potent substrate of the activated ALK kinase.
The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret (show RET Antibodies) to the phosphatidylinositol 3-kinase/Akt (show AKT1 Antibodies) signaling pathway.
ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma (show ARHGEF16 Antibodies) cells
The inappropriate in vivo expression of Shc3 in high-grade glioma may contribute to the survival of the cancer cells.
data suggest that RAI (ShcC/H-Shc (show SHC1 Antibodies))is a critical substrate for RET (show RET Antibodies) oncoproteins in thyroid carcinomas

Mouse (Murine) SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) interaction partners

The results provide evidence that Rai/ShcC plays opposite roles in Th17 cell differentiation and astrocyte activation
Rai (ShcC/N-Shc), a member of the family of Shc (show SHC1 Antibodies)-like adaptor proteins, as a new regulator of migration of normal and cancer stem/progenitor cells.
Rai interferes with the TCR signaling cascade one of the earliest steps--recruitment of the initiating kinase ZAP-70 (show ZAP70 Antibodies) to the phosphorylated subunit of the TCR/CD3 (show CD3E Antibodies) complex.
TrkB (show NTRK2 Antibodies)-mediated ERK1/2 activation is impaired in huntingtin (show HTT Antibodies) knock-in striatal cells involves reduced p52 (show GTF2H4 Antibodies)/p46 (show POLDIP3 Antibodies) Shc (show SHC1 Antibodies) expression
Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc (show SHC1 Antibodies).
binds the Trk (show NTRK1 Antibodies) receptors in a phosphotyrosine-dependent manner via their N-terminal phosphotyrosine binding domain
Rai has a functional neuroprotective role in brain injury, with possible implications in the treatment of stroke
ShcC mediates TrkB (show NTRK2 Antibodies)-Ras/MAPK (show MAPK1 Antibodies) signaling & regulates NMDA receptor function in the hippocampus via interaction with phosphotyrosines on the receptor subunits. It serves as a modulator of hippocampal synaptic plasticity underlying learning & memory.
ShcC has phosphotyrosine-dependent and -independent functions in neuroblastoma (show ARHGEF16 Antibodies) cells
Expressed in T and B cells; loss of Rai results in breaking of immunological tolerance and development of systemic autoimmunity.

SHC3 Antigen Profile

Antigen Summary

may be involved in brain-derived neurotrophic factor signalling during retinal development

Alternative names and synonyms associated with SHC3

SHC adaptor protein 3 (SHC3) antibody
SHC adaptor protein 3 (Shc3) antibody
src homology 2 domain-containing transforming protein C3 (Shc3) antibody

N-Shc antibody
NSHC antibody
Rai antibody
ShcC antibody

Protein level used designations for SHC3

SH2 domain protein C3 , SHC-transforming protein 3 , SHC-transforming protein C , neuronal Shc , protein Rai , src homology 2 domain-containing transforming protein C3 , src homology 2 domain-containing-transforming protein C3 , N-Shc

GENE ID	SPECIES
100061926	Equus caballus
53358	Homo sapiens
114858	Rattus norvegicus
476352	Canis lupus familiaris
20418	Mus musculus

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Show all anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) Antibodies with Pubmed References

Human SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) interaction partners

Mouse (Murine) SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) interaction partners

Antigen Summary

Alternative names and synonyms associated with SHC3

Protein level used designations for SHC3