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SARS-CoV-2 Spike S1 Proteins

(SARS-CoV-2 Spike S1)
attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651, PubMed:32075877, PubMed:32155444). Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry (PubMed:32142651). Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.

98 results

Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: Mammalian Cells Recombinant >80 % as determined by SDS-PAGE.
Catalog No. ABIN7825139
$544.25
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 14 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN7825143
$544.25
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 14 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: Mammalian Cells Recombinant >80 % as determined by SDS-PAGE.
Catalog No. ABIN7825140
$544.25
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 14 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: Mammalian Cells Recombinant >80 % as determined by SDS-PAGE.
Catalog No. ABIN7825141
$544.25
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 14 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: Mammalian Cells Recombinant >80 % as determined by SDS-PAGE.
Catalog No. ABIN7825142
$544.25
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 14 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN7825119
$544.25
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 14 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant >95 % (SDS-PAGE) Active
Catalog No. ABIN7566327
$620.43
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 5 to 8 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: Tobacco (Nicotiana benthamiana) Recombinant ≥ 85 %
Catalog No. ABIN7233212
$543.08
Plus shipping costs $50.00
100 μL
Shipping to: United States
Delivery in 11 to 12 Business Days
 
Origin: Coronavirus (CoV) Host: HEK-293 Cells Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Catalog No. ABIN7665354
$784.62
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 95 % by SDS - PAGE SDS, AcA Active
Catalog No. ABIN7677315
$806.15
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: Baculovirus infected Insect Cells Recombinant > 95 % SDS, AcA Active
Catalog No. ABIN7677289
$806.15
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 85 % SDS, AcA Active
Catalog No. ABIN7677285
$806.15
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: CHO Cells Recombinant >95 % as determined by SDS-PAGE and HPLC
Catalog No. ABIN6953024
$822.04
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 9 to 10 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant >85 % ELISA, LF
Catalog No. ABIN7385268
$948.30
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 3 to 4 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 95 % Inactive
Catalog No. ABIN7669700
$1,154.40
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 90 % ELISA Active
Catalog No. ABIN7669701
$1,154.40
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 95 % ELISA Active
Catalog No. ABIN7669703
$1,154.40
Plus shipping costs $50.00
20 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 90 % ELISA Active
Catalog No. ABIN7669705
$1,154.40
Plus shipping costs $50.00
20 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 85 % ELISA Active
Catalog No. ABIN7669707
$1,154.40
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 90 % ELISA Active
Catalog No. ABIN7669708
$1,154.40
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Affinity Measurement (AM)
    • Functional Studies (Func)
    • Immunoassay (IA)
    • Screening Assay (ScA)
    • Antibody Drug Assay (ADA)
    • Activity Assay (AcA)
    • Lateral Flow (LF)
    • Control (Ct)
    • Enzyme Immunoassay (EIA)
    • Immunogen (Imm)
    • Positive Control (PC)
  • Reactivity
    • SARS Coronavirus-2 (SARS-CoV-2)
    • SARS Coronavirus (SARS-CoV)
    • SARS CoV-2 Beta
    • SARS CoV-2 Omicron
    • SARS CoV-2 Delta
    • Coronavirus (CoV)
    • SARS CoV-2 Alpha
  • Cited in publications
  • Images available
  • Preservative free only
  • Carrier free only
  • Host
    • HEK-293 Cells
    • Mammalian Cells
    • Escherichia coli (E. coli)
    • Insect Cells
    • Baculovirus infected Insect Cells
    • CHO Cells
    • Human Cells
    • Tobacco (Nicotiana benthamiana)
  • Binding Specificity
    • RBD
    • AA 14-683
    • AA 16-685
    • AA 319-541
    • D614G
    • N-Term
    • AA 14-667
    • AA 16-6
    • B.1.1.529 - Omicron
    • B.1.351 - beta
    • AA 1-674
    • AA 13-303
    • B.1.617.2 - delta
    • N501Y
    • AA 14-6
    • BA.4 - Omicron
    • BA.5 - Omicron
    • Extracellular Domain
    • Receptor Binding Domain
    • AA 1-305
    • AA 1-681
    • AA 1-685
    • AA 13-6
    • AA 14-685
    • AA 16-305
    • AA 315-535
    • AA 330-530
    • AA 334-527
    • Asp614Gly
    • B.1.1.7 - alpha
    • B.1.640.2
    • BA.2 - Omicron
    • BA.2.12.1 - Omicron
    • BA.2.75 - Omicron
    • BA.5.2 - Omicron
    • C-Term
    • C.37 - Lambda
    • E484K
    • G476S
    • K417N
    • NTD
    • P.1 - gamma
    • P.1.1 - Gamma
    • P.1.2 - Gamma
    • Subunit S1
    • V367F
    • V483A
    • W436R
  • Conjugate
    • His tag
    • Fc Tag
    • mFc Tag
    • His tag,AVI tag,Biotin
    • His-Avi Tag
    • Biotin,His-Avi Tag
    • hFc-Avi Tag
    • hFc-Avi Tag,Biotin
    • Un-conjugated
    • Biotin
    • Fc-Avi Tag
    • Fc-His Tag
    • GST tag,His tag
    • His tag,Biotin
    • His tag,Fc Tag
    • His tag,SEKDEL Tag
    • His-Avi Tag,Biotin
    • His-DYKDDDDK Tag
    • hFc Tag
    • sFc-Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
    • Biologically Inactive
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • ProSci
    • RayBiotech

Latest Publications for our SARS-CoV-2 Spike S1 Proteins

Erickson, Logsdon, Rhea, Hansen, Holden, Banks, Smith, German, Farr, Morley, Weaver, Hirsch, Kovac, Kontsekova, Baumann, Omer, Raber: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).

Fan, Parr, Kang, Gupta: "Point-of-care (POC) SARS-CoV-2 antigen detection using functionalized aerosol jet-printed organic electrochemical transistors (OECTs)." in: Nanoscale, Vol. 15, Issue 11, pp. 5476-5485, (2023) (PubMed).

Kaneko, Satta, Komuro, Muthukrishnan, Kakarla, Guo, An, Elahi, Kornblum, Liebeskind, Hsiai, Hinman: "Flow-Mediated Susceptibility and Molecular Response of Cerebral Endothelia to SARS-CoV-2 Infection." in: Stroke, Vol. 52, Issue 1, pp. 260-270, (2021) (PubMed).

Sasisekharan, Pentakota, Jayaraman, Tharakaraman, Wogan, Narayanasami: "Orthogonal immunoassays for IgG antibodies to SARS-CoV-2 antigens reveal that immune response lasts beyond 4 mo post illness onset." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Issue 5, (2021) (PubMed).

Dogan, Kozhaya, Placek, Gunter, Yigit, Hardy, Plassmeyer, Coatney, Lillard, Bukhari, Kleinberg, Hayes, Arditi, Klapper, Merin, Liang, Gupta, Alpan, Unutmaz: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." in: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).

Narang, James, Balmer, Wilson: "Protein Footprinting, Conformational Dynamics, and Core Interface-Adjacent Neutralization "Hotspots" in the SARS-CoV-2 Spike Protein Receptor Binding Domain/Human ACE2 Interaction." in: Journal of the American Society for Mass Spectrometry, (2021) (PubMed).

Fiedler, Piziorska, Denninger, Morgunov, Ilsley, Malik, Schneider, Devenish, Meisl, Kosmoliaptsis, Aguzzi, Fiegler, Knowles: "Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum." in: ACS infectious diseases, (2021) (PubMed).

Lucas, Klein, Sundaram, Liu, Wong, Silva, Mao, Oh, Mohanty, Huang, Tokuyama, Lu, Venkataraman, Park, Israelow, Vogels, Muenker, Chang, Casanovas-Massana, Moore, Zell, Fournier, Wyllie, Campbell, Lee et al.: "Delayed production of neutralizing antibodies correlates with fatal COVID-19. ..." in: Nature medicine, (2021) (PubMed).

Song, Bartley, Chow, Ngo, Jiang, Zamecnik, Dandekar, Loudermilk, Dai, Liu, Sunshine, Liu, Wu, Hawes, Alvarenga, Huynh, McAlpine, Rahman, Geng, Chiarella, Goldman-Israelow, Vogels, Grubaugh et al.: "Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms. ..." in: Cell reports. Medicine, pp. 100288, (2021) (PubMed).

Guo, Huang, Zhang, Yao, Zhou, Shen, Shen, Li, Li, Zhang, Chen, Chen, Wu, Fu, Zeng, Feng, Pi, Wang, Zhou, Lu, Li, Fang, Lu, Hu, Wang, Zhang, Gao, Adrian, Wang, Yu, Peng, Gabibov, Min, Wang, Huang et al.: "A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. ..." in: Nature communications, Vol. 12, Issue 1, pp. 2623, (2021) (PubMed).

Aliases for SARS-CoV-2 Spike S1 Proteins

Surface Glycoprotein (S) Proteins
E2 Proteins
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