(serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008].
serpin A3-5 (LOC396684) Proteins serpin family A member 3 (SERPINA3) Proteins alpha-1-antiproteinase F precursor (LOC100008973) Proteins serpin family A member 1 (SERPINA1) Proteins serpin family A member 1 (Serpina1) Proteins serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SPIA5) Proteins serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3) Proteins serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog (serpina3.L) Proteins A1AT Proteins AACT Proteins AAT Proteins ACT Proteins alpha-1-PI Proteins GIG25 Proteins PI Proteins Pi Proteins Pi2 Proteins serpina3 Proteins SERPINA3-1 Proteins SERPINA3-5 Proteins Spi1 Proteins