SET Domain Containing (Lysine Methyltransferase) 8 Proteins

(SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))

Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).

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11 results

SETD8 Protein (AA 1-349) (His tag)

custom-made SETD8 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Kmt5a Protein, UniprotID Q2YDW7

3 images

Catalog No. ABIN7563657

Details

SETD8 Protein (AA 1-393) (His tag)

custom-made SETD8 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant KMT5A Protein, UniprotID Q9NQR1

3 images

Catalog No. ABIN7554369

Details

SETD8 Protein (AA 195-352) (His tag)

SETD8 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

Western Blotting (WB) image for SET Domain Containing (Lysine Methyltransferase) 8 (SETD8) (AA 195-352) protein (His tag) (ABIN7125068)

1 image

Catalog No. ABIN7125068

Details

SETD8 Protein (His tag)

SETD8 Origin: Human Host: Escherichia coli (E. coli) Recombinant ELISA, WB, SDS

Catalog No. ABIN7577828

Details

SETD8 Protein (AA 195-352) (His tag)

SETD8 Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 85% by SDS-PAGE SDS

Catalog No. ABIN5855179

Details

SETD8 Protein (AA 1-349) (Strep Tag)

custom-made SETD8 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3134954

Details

SETD8 Protein (AA 1-393) (Strep Tag)

custom-made SETD8 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Catalog No. ABIN3093468