Mouse anti-Human IgM (Heavy Chain) Antibody (CF®488A)

Catalog No. ABIN7879460

Quick Overview for Mouse anti-Human IgM (Heavy Chain) Antibody (CF®488A) (ABIN7879460)

Target: IgM

Clonality: Monoclonal

Conjugate: CF®488A

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: IM373

Isotype: IgG2b, kappa

Product Details

Binding Specificity: Heavy Chain

Reactivity: Human

Host: Mouse

Purpose: IgM Heavy Chain Antibody

Purification: Protein G affinity chromatography

Immunogen: Recombinant heavy chain of human IgM was used as the immunogen for this antibody.

Application Details

Application Notes: Optimal dilution of the IgM Heavy Chain antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the IgM Heavy Chain antibody at 2-8oC, protected from light.

Target Details

Target: IgM

Target Type: Antibody

Background: This antibody recognizes a protein of 75 kDa, identified as the mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. The antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.