Recombinant Mouse anti-Human Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Antibody

Catalog No. ABIN7879477

Quick Overview for Recombinant Mouse anti-Human Immunoglobulin kappa Chain Complex (Igk) (Light Chain) Antibody (ABIN7879477)

Target: Igk (Immunoglobulin kappa Chain Complex (Igk))

Antibody Type: Recombinant Antibody

Clonality: Monoclonal

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: RKLC709

Isotype: IgG1, kappa

Product Details

Binding Specificity: Light Chain

Reactivity: Human

Host: Mouse

Purpose: Recombinant Anti-Kappa Light Chain Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Recombinant human Ig kappa chain was used as the immunogen for this recombinant anti-Kappa light chain antibody.

Application Details

Application Notes: The optimal dilution of the recombinant anti-Kappa light chain antibody for each application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant anti-Kappa light chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details

Target: Igk (Immunoglobulin kappa Chain Complex (Igk))

Alternative Name: Kappa

Background: This mAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

UniProt: P01601