SKA1 Proteins

(Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))

Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules (By similarity).

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SKA1 Protein (AA 1-254) (His tag)

custom-made SKA1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Ska1 Protein, UniprotID Q9CPV1

3 images

Catalog No. ABIN7560484

Details

SKA1 Protein (AA 1-255) (His tag)

SKA1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

Western Blotting (WB) image for Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (AA 1-255) protein (His tag) (ABIN7125191)

1 image

Catalog No. ABIN7125191

Details

SKA1 Protein

SKA1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % pure SDS

Catalog No. ABIN2131856

Details

SKA1 Protein (AA 1-254) (Strep Tag)

custom-made SKA1 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

Catalog No. ABIN3128201