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SLC22A2 Products

(Solute Carrier Family 22 (Organic Cation Transporter), Member 2 (SLC22A2))
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. [provided by RefSeq, Jul 2008].

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Featured SLC22A2 Categories

SLC22A2 Antibodies

High quality antibodies with extensive validation data.

SLC22A2 ELISA Kits

Reliable ELISA kits for a wide range of species.

SLC22A2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SLC22A2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7170144
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN6242877
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN2752447
Quantity 100 μg
Datasheet Datasheet

Recommended SLC22A2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648542
Quantity 96 tests
Datasheet Datasheet

Recommended SLC22A2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125158
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320205
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320207
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our SLC22A2 products

Schmitt, Schäll, Bucher, Schindler, Hector, Biedermann, Zemlin, Hartl, Beer-Hammer: "SLy2 controls the antibody response to pneumococcal vaccine through an IL-5Rα-dependent mechanism in B-1 cells." in: European journal of immunology, Vol. 45, Issue 1, pp. 60-70, (2015) (PubMed).

Li, Cui, Jiang, Guo, Pishdari, Hu, Feng, Billig, Shao: "Reversing the reduced level of endometrial GLUT4 expression in polycystic ovary syndrome: a mechanistic study of metformin action." in: American journal of translational research, Vol. 7, Issue 3, pp. 574-86, (2015) (PubMed).

Shao, Li, Feng, Lin, Billig: "Direct effects of metformin in the endometrium: a hypothetical mechanism for the treatment of women with PCOS and endometrial carcinoma." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 41, (2014) (PubMed).

Wang, Sun, Li, Tu, Jiang: "Involvement of organic cation transporter 2 inhibition in potential mechanisms of antidepressant action." in: Progress in neuro-psychopharmacology & biological psychiatry, Vol. 53, pp. 90-8, (2014) (PubMed).

Sprowl, Ciarimboli, Lancaster, Giovinazzo, Gibson, Du, Janke, Cavaletti, Shields, Sparreboom: "Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 27, pp. 11199-204, (2013) (PubMed).

Filipski, Loos, Verweij, Sparreboom: "Interaction of Cisplatin with the human organic cation transporter 2." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 12, pp. 3875-80, (2008) (PubMed).

Pelis, Suhre, Wright: "Functional influence of N-glycosylation in OCT2-mediated tetraethylammonium transport." in: American journal of physiology. Renal physiology, Vol. 290, Issue 5, pp. F1118-26, (2006) (PubMed).

Synonyms and alternative names related to SLC22A2

solute carrier family 22 member 2 (SLC22A2), solute carrier family 22 (organic cation transporter), member 2 (Slc22a2), solute carrier family 22 member 2 (Slc22a2), POU class 2 homeobox 2 (POU2F2), solute carrier family 22 member 2 (LOC521027), solute carrier family 22 (organic cation transporter), member 2 (SLC22A2), solute carrier family 22 (organic cation transporter), member 2 (slc22a2), solute carrier family 22 (organic cation transporter), member 2 L homeolog (slc22a2.L), oct1, OCT2, Oct2, OCT2P, OCT2r, Orct2, Pou2f2, rOCT2, slc22a2, wu:fc01b11, zgc:64076

Protein level used designations for SLC22A2

  • organic cation transporter 2
  • solute carrier family 22 member 2
  • solute carrier family 22, member 2
  • OTF-2
  • POU domain, class 2, transcription factor 2
  • lymphoid-restricted immunoglobulin octamer-binding protein NF-A2
  • oct-2
  • octamer-binding protein 2
  • octamer-binding transcription factor 2
  • apical organic cation transporter
  • Organic cation transporter 2
  • solute carrier family 22 (organic cation transporter), member 2
  • solute carrier family 22 (organic cation transporter), member 2 L homeolog
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