Slc6a20a Protein (AA 1-592) (His tag)
custom-made
SLC6A20A
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target
- Slc6a20a (SLC6A20A) (Solute Carrier Family 6 (Neurotransmitter Transporter), Member 20A (SLC6A20A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-592
- Origin
- Mouse
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Slc6a20a protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Slc6a20a Protein expressed in mammalian cells.
- Sequence
- MEKARPQWGH PLQFVFACIS YAVGLGNVWR FPYLCQMYGG GSFLVPYIIM LIVEGMPLLY LELAVGQRMR QGSIGAWRTI SPYLSGVGVA SVVVSFFLSM YYNVINAWGF WYLFHSFQDP LPWSVCPLNS NHTGYDEECE KASSTQYFWY RKTLNISPSI QENGGVQWEP ALCLTLAWLM VYLCILRGTE STGKVVYFTA SMPYCVLIIY LVRGLTLHGA TNGLMYMFTP KMEQLANPKA WINAATQIFF SLGLGFGSLI AFASYNEPSN NCQKHAIIVS IINSSTSIFA SIVTFSIYGF KATFNYENCL NKVILLLTNS FDLEDGFLTV SNLEEVKNYL ASTYPNKYSE VFPHIRNCSL ESELDTAVQG TGLAFIVYTE AIKNMEVSQL WSVLYFFMLL MLGIGSMLGN TAAILTPLTD SKVISSYLPK EAISGLVCLI NCAVGMVFTM EAGNYWFDIF NDYAATLSLL LIVLVETIAV CYVYGLKRFE SDLRAMTGRT LSWYWKVMWA FVSPLLIVGL FIFYLSDYIL TGTLQYQAWD ATQGQLVTKD YPPHALAVIG LLVASSTMCI PLVALGTFIR NRLKRGGSAP VA Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- Slc6a20a (SLC6A20A) (Solute Carrier Family 6 (Neurotransmitter Transporter), Member 20A (SLC6A20A))
- Alternative Name
- Slc6a20a
- Background
- Sodium- and chloride-dependent transporter XTRP3A (IMINO-B) (Solute carrier family 6 member 20A) (X transporter protein 3 similar 1),FUNCTION: Mediates the Na(+)- and Cl(-)-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids (PubMed:15689184). Also transports glycine, regulates proline and glycine homeostasis in the brain playing a role in the modulation of NMDAR currents (PubMed:33428810). {ECO:0000269|PubMed:15689184, ECO:0000269|PubMed:33428810}.
- Molecular Weight
- 66.2 kDa
- UniProt
- Q8VDB9
- AlphaFold
- Q8VDB9
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