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SNCA Proteins

(Synuclein, alpha (SNCA))
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].

53 results :

SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Catalog No. ABIN5651245
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active
Catalog No. ABIN5065829
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Catalog No. ABIN6952303
 
custom-made SNCA Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7544253
 
custom-made SNCA Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7562469
 
SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320688
 
SNCA Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Catalog No. ABIN7125301
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Catalog No. ABIN934871
 
SNCA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Catalog No. ABIN1320776
 
SNCA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Catalog No. ABIN1320774
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
Pubmed 3 references
Catalog No. ABIN1046507
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7504231
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505128
 
SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505351
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319207
 
SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN4371752
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA
Catalog No. ABIN7579612
 
SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, PC, Imm
Catalog No. ABIN7393487
 
SNCA Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, PC, Imm
Catalog No. ABIN7405657
 
custom-made SNCA Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
Catalog No. ABIN3131854
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • In vitro Assay (in vitro)
    • In vivo Studies (in vivo)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Cellular Assay (CA)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Standard (STD)
    • Immunoprecipitation (IP)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cynomolgus
    • Bonobo
    • Chimpanzee
    • Cow
    • Orang-Utan
    • Pig
    • Primate (Erythrocebus)
    • Red-chested mustached Tamarin (Saguinus labiatus)
    • Serinus canaria
    • Spider Monkey
    • Woolly Monkey
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
  • Binding Specificity
    • AA 1-140
    • full length
    • A53T
    • AA 23-140
    • AA 1-139
    • AA 1-143
    • AA 1-60
    • AA 31-140
    • AA 61-140
    • AA 96-140
    • E46K
    • R30P
    • Transcript Variant 2
    • Transcript Variant 3
    • active
    • partial
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag
    • Myc-DYKDDDDK Tag
    • Strep Tag
    • Biotin
    • Fc Tag
    • HiLyte Fluor 488
    • His tag,AVI tag,Biotin
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Grade
    • MALS verified
    • custom-made
  • Supplier
    • antibodies-online
    • CUSABIO
    • ACROBiosystems
    • Eurogentec
    • ITSI-Biosciences
    • OriGene
    • Signalway
    • Abbexa
    • Rockland

Latest Publications for our SNCA Proteins

Xu, Li, Qin, Zhu, Zhou, Shi, Wang, Hu, Fan, Li: "Unraveling the role of hydrogen peroxide in ?-synuclein aggregation using an ultrasensitive nanoplasmonic probe." in: Analytical chemistry, Vol. 87, Issue 3, pp. 1968-73, (2015) (PubMed).

Jüttner, Moré, Das, Babich, Meier, Henning, Erdmann, Mu Ller, Otto, Grantyn, Rathjen: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." in: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).

Uéda, Saitoh, Mori: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." in: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).

Campion, Martin, Heilig, Charbonnier, Moreau, Flaman, Petit, Hannequin, Brice, Frebourg: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." in: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).

Uéda, Fukushima, Masliah, Xia, Iwai, Yoshimoto, Otero, Kondo, Ihara, Saitoh: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).

Aliases for SNCA Proteins

synuclein alpha L homeolog (snca.L) Proteins
alpha-synuclein (LOC619283) Proteins
synuclein alpha (SNCA) Proteins
synuclein, alpha (Snca) Proteins
synuclein alpha (Snca) Proteins
alphaSYN Proteins
LOC619283 Proteins
MGC64356 Proteins
NACP Proteins
PARK1 Proteins
PARK4 Proteins
PD1 Proteins
snca Proteins
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