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SNCA Proteins

(Synuclein, alpha (SNCA))
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].

57 results

SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % Inactive
Catalog No. ABIN7669811
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % Inactive
Catalog No. ABIN7669810
 
SNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % Inactive
Catalog No. ABIN7669809
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % Inactive
Catalog No. ABIN7669812
 
custom-made SNCA Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
Catalog No. ABIN3131854
 
custom-made SNCA Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA
Catalog No. ABIN3073847
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5710386
 
SNCA Origin: Human Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN5713850
 
SNCA Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
Catalog No. ABIN3011795
 
SNCA Origin: Cynomolgus Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7479347
 
SNCA Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7586177
 
SNCA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714638
 
SNCA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714639
 
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN6972940
 
Rockland 009-001-t45s SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant >95% WB
Catalog No. ABIN6700593
Rockland Original
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant CA
Catalog No. ABIN1882770
 
MALS verified SNCA Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN7271629
 
MALS verified SNCA Origin: Cynomolgus Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN7273444
 
SNCA Origin: Human Recombinant
Catalog No. ABIN1061360
 
SNCA Origin: Human Recombinant
Catalog No. ABIN1061348
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • In vitro Assay (in vitro)
    • In vivo Studies (in vivo)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Standard (STD)
    • Cellular Assay (CA)
    • Immunoprecipitation (IP)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cynomolgus
    • Bonobo
    • Chimpanzee
    • Cow
    • Orang-Utan
    • Pig
    • Primate (Erythrocebus)
    • Red-chested mustached Tamarin (Saguinus labiatus)
    • Serinus canaria
    • Spider Monkey
    • Woolly Monkey
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
  • Binding Specificity
    • AA 1-140
    • full length
    • A53T
    • AA 23-140
    • AA 1-139
    • AA 1-143
    • AA 1-60
    • AA 31-140
    • AA 61-140
    • AA 96-140
    • E46K
    • K23Q
    • R30P
    • Transcript Variant 2
    • Transcript Variant 3
    • active
    • partial
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag
    • Myc-DYKDDDDK Tag
    • Strep Tag
    • Biotin
    • Fc Tag
    • HiLyte Fluor 488
    • His tag,AVI tag,Biotin
    • His-IF2DI Tag
    • TRX tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
    • Biologically Inactive
  • Grade
    • MALS verified
    • custom-made
  • Supplier
    • antibodies-online
    • CUSABIO
    • ACROBiosystems
    • ITSI-Biosciences
    • Eurogentec
    • OriGene
    • Signalway
    • Abbexa
    • Rockland

Latest Publications for our SNCA Proteins

Xu, Li, Qin, Zhu, Zhou, Shi, Wang, Hu, Fan, Li: "Unraveling the role of hydrogen peroxide in ?-synuclein aggregation using an ultrasensitive nanoplasmonic probe." in: Analytical chemistry, Vol. 87, Issue 3, pp. 1968-73, (2015) (PubMed).

Jüttner, Moré, Das, Babich, Meier, Henning, Erdmann, Mu Ller, Otto, Grantyn, Rathjen: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." in: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).

Uéda, Saitoh, Mori: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." in: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).

Campion, Martin, Heilig, Charbonnier, Moreau, Flaman, Petit, Hannequin, Brice, Frebourg: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." in: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).

Uéda, Fukushima, Masliah, Xia, Iwai, Yoshimoto, Otero, Kondo, Ihara, Saitoh: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).

Aliases for SNCA Proteins

synuclein alpha L homeolog (snca.L) Proteins
alpha-synuclein (LOC619283) Proteins
synuclein alpha (SNCA) Proteins
synuclein, alpha (Snca) Proteins
synuclein alpha (Snca) Proteins
alphaSYN Proteins
LOC619283 Proteins
MGC64356 Proteins
NACP Proteins
PARK1 Proteins
PARK4 Proteins
PD1 Proteins
snca Proteins
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