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SPEG Products

(SPEG Complex Locus (SPEG))

Categories

This gene encodes a protein with similarity to members of the myosin light chain kinase family. This protein family is required for myocyte cytoskeletal development. Studies in mouse have determined that a lack of this protein affected myocardial development. Multiple alternatively spliced transcript variants have been reported for this gene, but the full-length nature of only two variants that encode different protein isoforms has been defined. [provided by RefSeq, Mar 2010].

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Featured SPEG Categories

SPEG Antibodies

High quality antibodies with extensive validation data.

SPEG Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SPEG Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN564467
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN523702
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN523701
Quantity 50 μL
Datasheet Datasheet

Recommended SPEG ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6951561
Quantity 96 tests
Datasheet Datasheet

Recommended SPEG Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321143
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321141
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7198099
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our SPEG products

Agrawal, Pierson, Joshi, Liu, Ravenscroft, Moghadaszadeh, Talabere, Viola, Swanson, Haliloğlu, Talim, Yau, Allcock, Laing, Perrella, Beggs: "SPEG interacts with myotubularin, and its deficiency causes centronuclear myopathy with dilated cardiomyopathy." in: American journal of human genetics, Vol. 95, Issue 2, pp. 218-26, (2014) (PubMed).

Hsieh, Yoshizumi, Endege, Kho, Jain, Kashiki, de los Santos, Lee, Perrella, Lee: "APEG-1, a novel gene preferentially expressed in aortic smooth muscle cells, is down-regulated by vascular injury." in: The Journal of biological chemistry, Vol. 271, Issue 29, pp. 17354-9, (1996) (PubMed).

Synonyms and alternative names related to SPEG

SPEG complex locus a (spega), SPEG complex locus (SPEG), SPEG complex locus (Speg), APEG-1, apeg1, APEG1, Apeg1, AW125581, BPEG, D1Bwg1450e, fc31c10, im:6912258, mKIAA1297, SPEGalpha, SPEGbeta, wu:fc31c10

Protein level used designations for SPEG

  • aortic preferentially expressed gene 1
  • novel serine/threonine protein kinase
  • striated muscle preferentially expressed protein kinase
  • aortic preferentially expressed protein 1
  • nuclear protein, marker for differentiated aortic smooth muscle and down-regulated with vascular injury
  • APEG-1
  • striated muscle-specific serine/threonine-protein kinase
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