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STEAP2 Products

(STEAP Family Member 2, Metalloreductase (STEAP2))
This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Featured STEAP2 Categories

STEAP2 Antibodies

High quality antibodies with extensive validation data.

STEAP2 ELISA Kits

Reliable ELISA kits for a wide range of species.

STEAP2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended STEAP2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN651772
Quantity 400 μL
Datasheet Datasheet
Reactivity Bat, Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Rabbit, Rat
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN960821
Quantity 50 μg
Datasheet Datasheet
Reactivity Bat, Cow, Human
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN960822
Quantity 50 μg
Datasheet Datasheet

Recommended STEAP2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959714
Quantity 96 tests
Datasheet Datasheet

Recommended STEAP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7491745
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321628
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321626
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our STEAP2 products

Ohgami, Campagna, McDonald, Fleming: "The Steap proteins are metalloreductases." in: Blood, Vol. 108, Issue 4, pp. 1388-94, (2006) (PubMed).

Ohgami, Campagna, Greer, Antiochos, McDonald, Chen, Sharp, Fujiwara, Barker, Fleming: "Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells." in: Nature genetics, Vol. 37, Issue 11, pp. 1264-9, (2005) (PubMed).

Porkka, Helenius, Visakorpi: "Cloning and characterization of a novel six-transmembrane protein STEAP2, expressed in normal and malignant prostate." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 82, Issue 11, pp. 1573-82, (2002) (PubMed).

Synonyms and alternative names related to STEAP2

six transmembrane epithelial antigen of prostate 2 (Steap2), STEAP2 metalloreductase (STEAP2), STEAP2 metalloreductase (Steap2), 4921538B17Rik, AI930049, AW045895, IPCA-1, IPCA1, PCANAP1, PUMPCn, STAMP1, STMP

Protein level used designations for STEAP2

  • metalloreductase STEAP2
  • six-transmembrane epithelial antigen of prostate 2
  • SixTransMembrane Protein of Prostate 1
  • prostate cancer associated protein 1
  • prostate cancer-associated protein 1
  • protein up-regulated in metastatic prostate cancer
  • protein upregulated in metastatic prostate cancer
  • six transmembrane epithelial antigen of prostate 2
  • six transmembrane epithelial antigen of the prostate 2
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