Suppression of Tumorigenicity 14 (Colon Carcinoma) Products
(Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))
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The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008].
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Featured Suppression of Tumorigenicity 14 (Colon Carcinoma) Categories
Suppression of Tumorigenicity 14 (Colon Carcinoma) Antibodies
High quality antibodies with extensive validation data.
Suppression of Tumorigenicity 14 (Colon Carcinoma) ELISA Kits
Reliable ELISA kits for a wide range of species.
Suppression of Tumorigenicity 14 (Colon Carcinoma) Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Suppression of Tumorigenicity 14 (Colon Carcinoma) Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN669726
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6263143
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN652185
Quantity
400 μL
Datasheet
Datasheet
Recommended Suppression of Tumorigenicity 14 (Colon Carcinoma) ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959763
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883709
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6386252
Quantity
96 tests
Datasheet
Datasheet
Recommended Suppression of Tumorigenicity 14 (Colon Carcinoma) Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7563458
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7555645
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1321472
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our Suppression of Tumorigenicity 14 (Colon Carcinoma) products
: "Developmental mechanisms driving complex tooth shape in reptiles." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 249, Issue 4, pp. 441-464, (2020) (PubMed).: "Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis." in: PLoS genetics, Vol. 15, Issue 1, pp. e1007882, (2019) (PubMed).
: "Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis." in: The Journal of biological chemistry, Vol. 292, Issue 26, pp. 10801-10812, (2017) (PubMed).
: "Matriptase zymogen supports epithelial development, homeostasis and regeneration." in: BMC biology, Vol. 15, Issue 1, pp. 46, (2017) (PubMed).
: "Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin." in: The Journal of biological chemistry, Vol. 291, Issue 6, pp. 2577-82, (2016) (PubMed).
: "Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling." in: Nature communications, Vol. 6, pp. 6776, (2015) (PubMed).
: "Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors." in: Oncogene, Vol. 34, Issue 35, pp. 4664-72, (2015) (PubMed).
: "Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma." in: The Journal of investigative dermatology, Vol. 135, Issue 9, pp. 2283-91, (2015) (PubMed).
: "Regulation of feto-maternal barrier by matriptase- and PAR-2-mediated signaling is required for placental morphogenesis and mouse embryonic survival." in: PLoS genetics, Vol. 10, Issue 7, pp. e1004470, (2015) (PubMed).
: "Matriptase proteolytically activates influenza virus and promotes multicycle replication in the human airway epithelium." in: Journal of virology, Vol. 87, Issue 8, pp. 4237-51, (2013) (PubMed).
Synonyms and alternative names related to Suppression of Tumorigenicity 14 (Colon Carcinoma)
suppression of tumorigenicity 14 (ST14), suppression of tumorigenicity 14 L homeolog (st14.L), suppression of tumorigenicity 14 (colon carcinoma) (St14), suppression of tumorigenicity 14 (St14), suppression of tumorigenicity 14 (colon carcinoma) a (st14a), suppression of tumorigenicity 14 (colon carcinoma) b (st14b), suppression of tumorigenicity 14 S homeolog (st14.S), Epithin, HAI, hai, matriptase, mCAP3, MT-SP1, mt-sp1, MTSP1, mtsp1, PRSS14, prss14, Prss14, SNC19, snc19, st14, st14-a, st14-b, st14a, st14b, TADG15, tadg15, tmprss1, TMPRSS14, Tmprss14, wu:fi41g07, wu:fl72f01, XMT-SP1, zgc:136950, zgc:152656, zgc:152657, zgc:152947Protein level used designations for Suppression of Tumorigenicity 14 (Colon Carcinoma)
- membrane-type serine protease 1
- prostamin
- serine protease 14
- serine protease TADG-15
- suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
- suppressor of tumorigenicity 14 protein
- tumor associated differentially expressed gene 15 protein
- tumor-associated differentially-expressed gene 15 protein
- matriptase a
- suppression of tumorigenicity 14 (colon carcinoma) a
- matriptase/MT-SP1
- protease, serine, 14 (epithin)
- suppressor of tumorigenicity 14 protein homolog
- matriptase
- membrane-type serine protease
- suppressor of tumorigenicity protein 14
- epithin
- matriptase 1a
- matriptase 1b
- matripase b
- suppression of tumorigenicity 14 (colon carcinoma) b
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