TBXAS1 Products
(thromboxane A Synthase 1 (Platelet) (TBXAS1))
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
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Featured TBXAS1 Categories
TBXAS1 Antibodies
High quality antibodies with extensive validation data.
TBXAS1 ELISA Kits
Reliable ELISA kits for a wide range of species.
TBXAS1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended TBXAS1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IHC (p), FACS
Validations
- (6)
Cat. No.
ABIN1501383
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC, IF, IHC (p), FACS
Validations
- (8)
Cat. No.
ABIN1501382
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p)
Validations
- (3)
Cat. No.
ABIN752623
Quantity
100 μL
Datasheet
Datasheet
Recommended TBXAS1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970643
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970644
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative
Validations
Cat. No.
ABIN773919
Quantity
96 tests
Datasheet
Datasheet
Recommended TBXAS1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1322310
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3073846
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3073845
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our TBXAS1 products
: "Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 8, pp. 1168-1182, (2019) (PubMed).: "Downregulation of TBXAS1 in an iron-induced malignant mesothelioma model." in: Cancer science, Vol. 106, Issue 10, pp. 1296-302, (2015) (PubMed).
: "Functional role of the conserved i-helix residue I346 in CYP5A1-Nanodiscs." in: Biophysical chemistry, Vol. 200-201, pp. 34-40, (2015) (PubMed).
: "Glycyrrhizin suppresses lung adenocarcinoma cell growth through inhibition of thromboxane synthase." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 33, Issue 2, pp. 375-88, (2014) (PubMed).
: "Functional investigations of thromboxane synthase (CYP5A1) in lipid bilayers of nanodiscs." in: Chembiochem : a European journal of chemical biology, Vol. 15, Issue 6, pp. 892-9, (2014) (PubMed).
: "18β-Glycyrrhetinic acid suppresses cell proliferation through inhibiting thromboxane synthase in non-small cell lung cancer." in: PLoS ONE, Vol. 9, Issue 4, pp. e93690, (2014) (PubMed).
Synonyms and alternative names related to TBXAS1
thromboxane-A synthase (PTRG_00454), thromboxane-A synthase (PTRG_06796), Thromboxane-A synthase (thas), thromboxane A synthase 1 (TBXAS1), thromboxane A synthase 1 (platelet) (tbxas1), thromboxane A synthase 1, platelet (Tbxas1), thromboxane A synthase 1 (Tbxas1), BDPLT14, CYP5, CYP5A1, GHOSAL, TBXAS1, thas, THAS, TS, TXAS, TXS, wu:fk19d08, zgc:136708Protein level used designations for TBXAS1
- thromboxane-A synthase
- Thromboxane-A synthase
- thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A)
- thromboxane A synthase 1 (platelet)
- thromboxane-A synthase-like
- TXA synthase
- cytochrome P450 5A1
- cytochrome P450, family 5, subfamily A, polypeptide 1
- platelet, cytochrome P450, subfamily V
- TXS
- thromboxane A synthase 1, platelet
- ThromboxA ane synthase 1
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