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Full name:: Primase, DNA, Polypeptide 2 (58kDa) Proteins (PRIM2)

On www.antibodies-online.com are 5 Primase, DNA, Polypeptide 2 (58kDa) (PRIM2) Proteins from 4 different suppliers available. Additionally we are shipping Primase, DNA, Polypeptide 2 (58kDa) Antibodies (39) and Primase, DNA, Polypeptide 2 (58kDa) Kits (7) and many more products for this protein. A total of 54 Primase, DNA, Polypeptide 2 (58kDa) products are currently listed.

Synonyms:: AI323589, p58, Pola3, PRIM2A

list all proteins	Gene Name	GeneID	UniProt
	PRIM2	19076	P33610
	PRIM2	301323
	PRIM2	5558	P49643
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Human Primase, DNA, Polypeptide 2 (58kDa) (PRIM2) interaction partners

Data suggest that PRIM1 (show PRIM1 Proteins)-p58 (show CDK11B Proteins),C-terminal domain stays bound to initiating NTP and 3prime-overhang DNA during whole cycle of RNA primer synthesis; meanwhile, PRIM1-p49 (show PRIM1 Proteins) slides along DNA template toward 5prime-end with PRIM1 (show PRIM1 Proteins)-p58 (show CDK11B Proteins),N-terminal domain attached.
the N-terminal domain of the large subunit of primase (p58N) directly interacts with the C-terminal domain of the catalytic subunit of polalpha (p180C)
PRIM2 gene is not imprinted in the placenta.
The fragment that forms a beta (show SUCLA2 Proteins)-sheet in the reported structure p58C/3L9Q of the same human primase domain is folded in three alpha-helices in our p58C/3Q36 structure, similarly to yeast primase.
analysis of the iron-sulfur cluster in the C-terminal domain of the p58 (show CDK11B Proteins) subunit of human DNA primase

Primase, DNA, Polypeptide 2 (58kDa) (PRIM2) Protein Profile

Protein Summary

The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the large, 58 kDa primase subunit.

Alternative names and synonyms associated with Primase, DNA, Polypeptide 2 (58kDa) (PRIM2)

DNA primase subunit 2 (prim2)
DNA primase, p58 subunit (Prim2)
DNA primase subunit 2 (Prim2)
DNA primase subunit 2 (PRIM2)

AI323589 protein
p58 protein
Pola3 protein
PRIM2A protein

Protein level used designations for PRIM2

DNA primase, p58 subunit , DNA primase 58 kDa subunit , DNA primase large subunit , DNA polymerase alpha subunit III (primase) , p58 , DNA primase subunit p58 , dJ422B11.1.1 , primase polypeptide 2A, 58kDa , primase, polypeptide 2A, 58kDa , DNA primase polypeptide 2

GENE ID	SPECIES
548762	Xenopus (Silurana) tropicalis
19076	Mus musculus
301323	Rattus norvegicus
5558	Homo sapiens
474950	Canis lupus familiaris
514682	Bos taurus

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