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TLR1 Products

(Toll-Like Receptor 1 (TLR1))
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008].

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Featured TLR1 Categories

TLR1 Antibodies

High quality antibodies with extensive validation data.

TLR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

TLR1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TLR1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (9)
Cat. No. ABIN3023655
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN736373
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7428071
Quantity 100 μL
Datasheet Datasheet

Recommended TLR1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6960024
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970733
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960025
Quantity 96 tests
Datasheet Datasheet

Recommended TLR1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322866
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322864
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3074242
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TLR1 products

Hellwing, Schoeniger, Roessler, Leimert, Schumann: "Lipid raft localization of TLR2 and its co-receptors is independent of membrane lipid composition." in: PeerJ, Vol. 6, pp. e4212, (2018) (PubMed).

Li, Yu, Li, Liu, Jiao, Song, Lv, Qin: "Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 5843, (2017) (PubMed).

Huhta, Helminen, Kauppila, Salo, Porvari, Saarnio, Lehenkari, Karttunen: "The Expression of Toll-like Receptors in Normal Human and Murine Gastrointestinal Organs and the Effect of Microbiome and Cancer." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 64, Issue 8, pp. 470-82, (2017) (PubMed).

Huhta, Helminen, Lehenkari, Saarnio, Karttunen, Kauppila: "Toll-like receptors 1, 2, 4 and 6 in esophageal epithelium, Barrett's esophagus, dysplasia and adenocarcinoma." in: Oncotarget, Vol. 7, Issue 17, pp. 23658-67, (2016) (PubMed).

Whitmore, Hook, Philiph, Hilkin, Bing, Ahn, Wong, Ferguson, Moreland: "A Common Genetic Variant in TLR1 Enhances Human Neutrophil Priming and Impacts Length of Intensive Care Stay in Pediatric Sepsis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 3, pp. 1376-86, (2016) (PubMed).

Jeon, Kim, Koh, Chung, Ha: "Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination." in: Oncotarget, Vol. 7, Issue 27, pp. 41811-41824, (2016) (PubMed).

Xi, Shao, Bai, Cai, Lv, Chen: "Changes in the expression of the Toll-like receptor system in the aging rat kidneys." in: PLoS ONE, Vol. 9, Issue 5, pp. e96351, (2014) (PubMed).

Adami, Yeung, Stucki, Kolokythas, Sroussi, Cabay, Kuzin, Schwartz: "Gene expression based evidence of innate immune response activation in the epithelium with oral lichen planus." in: Archives of oral biology, Vol. 59, Issue 3, pp. 354-61, (2014) (PubMed).

Hennig, Ilginus, Boztug, Skokowa, Marodi, Szaflarska, Sass, Pignata, Kilic, Caragol, Baumann, Klein, Welte, Hansen: "High-content cytometry and transcriptomic biomarker profiling of human B-cell activation." in: The Journal of allergy and clinical immunology, Vol. 133, Issue 1, pp. 172-80.e1-10, (2014) (PubMed).

Abdi, Mutis, Garssen, Redegeld: "Characterization of the Toll-like receptor expression profile in human multiple myeloma cells." in: PLoS ONE, Vol. 8, Issue 4, pp. e60671, (2013) (PubMed).

Synonyms and alternative names related to TLR1

toll like receptor 1 (TLR1), toll-like receptor 1 (Tlr1), toll-like receptor 1 (TLR1), CD281, rsc786, TIL, TIL. LPRS5

Protein level used designations for TLR1

  • toll/interleukin-1 receptor-like protein
  • TIL
  • Toll-like receptor 1 long form
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