TLR4 Proteins
(Toll-Like Receptor 4 (TLR4))
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
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20 results
TLR4
Origin: Human
Host: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
2 references
TLR4
Origin: Human
Host: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
TLR4
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
TLR4
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
TLR4
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
TLR4
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
TLR4
Origin: Goat
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
TLR4
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
TLR4
Origin: Cow
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
TLR4
Origin: Human
Host: Baculovirus infected Insect Cells
Recombinant
> 87 % as determined by reducing SDS-PAGE.
TLR4
Origin: Human
Host: HEK-293 Cells
Synthetic Nanodisc
Imm, ELISA, cryo-EM, PhD, SPR
TLR4
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
TLR4
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
TLR4
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our TLR4 Proteins
: "CD200 restrains macrophage attack on oligodendrocyte precursors via toll-like receptor 4 downregulation." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, (2015) (PubMed).: "Analysis of mechanistic pathway models in drug discovery: p38 pathway." in: Biotechnology progress, Vol. 24, Issue 1, pp. 96-109, (2008) (PubMed).
Aliases for TLR4 Proteins
toll like receptor 4 (TLR4) Proteinstoll-like receptor 4 (Tlr4) Proteins
toll like receptor 4 (Tlr4) Proteins
ARMD10 Proteins
CD284 Proteins
Lps Proteins
Ly87 Proteins
Ran/M1 Proteins
Rasl2-8 Proteins
TLR-4 Proteins
TOLL Proteins
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