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TNFSF9 Proteins

(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008].

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  • Target: TNFSF9
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN7960817
TNFSF9 Protein (His tag) TNFSF9 · Protein Human Escherichia coli (E. coli)
$664.40 View price
  • 50 μg
  • 1 mg
  • 500 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7953977
TNFSF9 Protein (His tag) TNFSF9 · Protein Mouse Escherichia coli (E. coli)
  • WB (Western Blotting: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • ELISA (ELISA: Listed application)
  • Imm (Immunogen: Listed application)
$478.00 View price
  • 100 μg
  • 1 mg
  • 50 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7951309
TNFSF9 Protein (His tag) TNFSF9 · Protein Human Mammalian Cells
  • WB (Western Blotting: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • ELISA (ELISA: Listed application)
  • Imm (Immunogen: Listed application)
$705.00 View price
  • 100 μg
  • 1 mg
  • 50 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7961643
TNFSF9 Protein (His tag) TNFSF9 · Protein Mouse Human Cells
$664.40 View price
  • 50 μg
  • 1 mg
  • 500 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7961615
TNFSF9 Protein (Fc Tag) TNFSF9 · Protein Human Human Cells
$554.40 View price
  • 50 μg
  • 1 mg
  • 500 μg
Delivery in 8 to 12 Business Days Shipping to: United States
ABIN7820313
TNFSF9 Protein (AA 147-309) (His tag) TNFSF9 · Protein Mouse Bacteria
$426.25 View price
  • 100 μg
Delivery in 7 to 10 Business Days Shipping to: United States
Protein
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7960817
$664.40
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
  • WB (Western Blotting: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • ELISA (ELISA: Listed application)
  • Imm (Immunogen: Listed application)
Origin
Mouse
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Catalog No. ABIN7953977
$478.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
  • WB (Western Blotting: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • ELISA (ELISA: Listed application)
  • Imm (Immunogen: Listed application)
Origin
Human
Host
Mammalian Cells
Protein Type
Recombinant
Catalog No. ABIN7951309
$705.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
Origin
Mouse
Host
Human Cells
Protein Type
Recombinant
Purity
Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7961643
$664.40
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
Origin
Human
Host
Human Cells
Protein Type
Recombinant
Purity
Greater than 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7961615
$554.40
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days
Protein
Origin
Mouse
Host
Bacteria
Protein Type
Recombinant
Catalog No. ABIN7820313
$426.25
Plus shipping costs $50.00, if applicable $20.00 dry ice
100 μg
Shipping to: United States
Delivery in 7 to 10 Business Days

Latest Publications for our TNFSF9 Proteins

Won, Cha, Byun, Kim, Shin, Ahn, Kim, Rice, Walz, Kwon, Cho: "The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily." in: The Journal of biological chemistry, Vol. 285, Issue 12, pp. 9202-10, (2010) (PubMed).

Rabu, Quéméner, Jacques, Echasserieau, Vusio, Lang: "Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity." in: The Journal of biological chemistry, Vol. 280, Issue 50, pp. 41472-81, (2005) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Xu, Zhang, Han, Zhang: "[Binding between alpha 1A-adrenergic receptor and segment of bone morphogenetic protein-1 in human embryonic cell 293]." in: Sheng li xue bao : [Acta physiologica Sinica], Vol. 55, Issue 6, pp. 692-8, (2003) (PubMed).

Alderson, Smith, Tough, Davis-Smith, Armitage, Falk, Roux, Baker, Sutherland, Din: "Molecular and biological characterization of human 4-1BB and its ligand." in: European journal of immunology, Vol. 24, Issue 9, pp. 2219-27, (1994) (PubMed).

Aliases for TNFSF9 Proteins

TNF superfamily member 9 (Tnfsf9) Proteins
TNF superfamily member 9 (LOC476729) Proteins
TNF superfamily member 9 (TNFSF9) Proteins
tumor necrosis factor (ligand) superfamily, member 9 (Tnfsf9) Proteins
4-1BB-L Proteins
4-1BBL Proteins
AI848817 Proteins
Cd137l Proteins
CD137L Proteins
Ly63l Proteins
TNFSF9 Proteins
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