TREM2 Antibodies

Abdi, Pasbakhsh, Shabani, Nekoonam, Sadeghi, Fathi, Abouzaripour, Mohamed, Zibara, Kashani, Zendedel: "Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis." in: Neurotoxicity research, (2021) (PubMed).

Hall, Agrawal: "Increased TREM-2 expression on the subsets of CD11c+ cells in the lungs and lymph nodes during allergic airway inflammation." in: Scientific reports, Vol. 7, Issue 1, pp. 11853, (2019) (PubMed).

Henjum, Quist-Paulsen, Zetterberg, Blennow, Nilsson, Watne: "CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Aβ42, t-tau and p-tau." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 304, (2019) (PubMed).

Zhong, Xu, Zhuo, Wang, Wang, Huang, Wang, Gao, Zhu, Sheng, Chen, Wang, Zhu, Can, Marten, Shinohara, Liu, Du, Sun, Wen, Xu, Bu, Chen: "Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model." in: Nature communications, Vol. 10, Issue 1, pp. 1365, (2019) (PubMed).

Jensen, Bahl, Østergaard, Høgh, Wermuth, Heslegrave, Zetterberg, Heegaard, Hasselbalch, Simonsen: "Exercise as a potential modulator of inflammation in patients with Alzheimer's disease measured in cerebrospinal fluid and plasma." in: Experimental gerontology, Vol. 121, pp. 91-98, (2019) (PubMed).

Nordengen, Kirsebom, Henjum, Selnes, Gísladóttir, Wettergreen, Torsetnes, Grøntvedt, Waterloo, Aarsland, Nilsson, Fladby: "Glial activation and inflammation along the Alzheimer's disease continuum." in: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 46, (2019) (PubMed).

Lee, Daggett, Gu, Jiang, Langfelder, Li, Wang, Zhao, Park, Cooper, Ferando, Mody, Coppola, Xu, Yang: "Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models." in: Neuron, Vol. 97, Issue 5, pp. 1032-1048.e5, (2019) (PubMed).

Zhao, Wu, Li, Jiang, Gui, Liu, Sun, Zhu, Piña-Crespo, Zhang, Zhang, Chen, Bu, An, Huang, Xu: "TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function." in: Neuron, Vol. 97, Issue 5, pp. 1023-1031.e7, (2019) (PubMed).

Cheng, Danao, Talreja, Wen, Yin, Sun, Li, Chui, Tran, Koirala, Chen, Foltz, Wang, Sambashivan: "TREM2-activating antibodies abrogate the negative pleiotropic effects of the Alzheimer's disease variant Trem2R47H on murine myeloid cell function." in: The Journal of biological chemistry, Vol. 293, Issue 32, pp. 12620-12633, (2018) (PubMed).

Zhao, Li, Huang, Jiang, Tan, Zhang, Cheng, Wang, Bu, Zhang, Wang, Xu: "Intracellular trafficking of TREM2 is regulated by presenilin 1." in: Experimental & molecular medicine, Vol. 49, Issue 12, pp. e405, (2018) (PubMed).