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TRIM25 Products

(Tripartite Motif Containing 25 (TRIM25))

Categories

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq, Jul 2008].

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Featured TRIM25 Categories

TRIM25 Antibodies

High quality antibodies with extensive validation data.

TRIM25 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended TRIM25 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (8)
Cat. No. ABIN5542675
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN521577
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7151322
Quantity 100 μg
Datasheet Datasheet

Recommended TRIM25 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648302
Quantity 96 tests
Datasheet Datasheet

Recommended TRIM25 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323635
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323637
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3096010
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TRIM25 products

Liu, Tao, Liao, Li, Li, Li, Lin, Wan, Yang, Chen: "TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway." in: Nature communications, Vol. 11, Issue 1, pp. 348, (2020) (PubMed).

Lian, Zang, Wei, Ye, Hu, Chen, Zhang, Guo, Lei, Yang, Luo, Li, Shu: "The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors." in: Immunity, Vol. 49, Issue 3, pp. 438-448.e5, (2018) (PubMed).

Urano, Saito, Tsukui, Fujita, Hosoi, Muramatsu, Ouchi, Inoue: "Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth." in: Nature, Vol. 417, Issue 6891, pp. 871-5, (2002) (PubMed).

Thomson, Ali, Pickles, Taylor, Pace, Lymboura, Shousha, Coombes: "Analysis of estrogen-responsive finger protein expression in benign and malignant human breast." in: International journal of cancer. Journal international du cancer, Vol. 91, Issue 2, pp. 152-8, (2001) (PubMed).

Orimo, Inoue, Minowa, Tominaga, Tomioka, Sato, Kuno, Hiroi, Shimizu, Suzuki, Noda, Muramatsu: "Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor alpha." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 21, pp. 12027-32, (1999) (PubMed).

Inoue, Orimo, Hosoi, Kondo, Toyoshima, Kondo, Ikegami, Ouchi, Orimo, Muramatsu: "Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11117-21, (1994) (PubMed).

Synonyms and alternative names related to TRIM25

E3 ubiquitin/ISG15 ligase TRIM25 (LOC100146440), tripartite motif containing 25 (trim25), E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog (LOC100490741.L), tripartite motif containing 25 (TRIM25), microRNA 3614 (MIR3614), tripartite motif-containing 25 (Trim25), AA960166, AL022677, EFP, Efp, MGC130751, RNF147, Z147, Zfp147, zgc:55773, ZNF147, Znf147

Protein level used designations for TRIM25

  • tripartite motif-containing 25
  • E3 ubiquitin/ISG15 ligase TRIM25
  • tripartite motif containing 25
  • RING finger protein 147
  • estrogen-responsive finger protein
  • tripartite motif protein TRIM25
  • tripartite motif-containing protein 25
  • ubiquitin/ISG15-conjugating enzyme TRIM25
  • zinc finger protein 147 (estrogen-responsive finger protein)
  • zinc finger protein-147
  • tripartite motif protein 25
  • zinc finger protein 147
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