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UBE2C Products

(Ubiquitin-Conjugating Enzyme E2C (UBE2C))
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].

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Featured UBE2C Categories

UBE2C Antibodies

High quality antibodies with extensive validation data.

UBE2C ELISA Kits

Reliable ELISA kits for a wide range of species.

UBE2C Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended UBE2C Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (8)
  • (7)
Cat. No. ABIN564800
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (6)
Cat. No. ABIN5542503
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (5)
Cat. No. ABIN6149787
Quantity 100 μL
Datasheet Datasheet

Recommended UBE2C ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971049
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960353
Quantity 96 tests
Datasheet Datasheet

Recommended UBE2C Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125607
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324332
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324336
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our UBE2C products

Castelblanco, Zafon, Maravall, Gallel, Martinez, Capel, Bella, Halperin, Temprana, Iglesias, Puig-Domingo, Robledo, Matias-Guiu, Mauricio: "APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions." in: Thyroid : official journal of the American Thyroid Association, Vol. 27, Issue 1, pp. 59-66, (2016) (PubMed).

Chou, Huang, Jhuang, Pan, Peng, Cheng, Chen, Chen, Chang: "Ubiquitin-conjugating enzyme UBE2C is highly expressed in breast microcalcification lesions." in: PLoS ONE, Vol. 9, Issue 4, pp. e93934, (2014) (PubMed).

Fristrup, Birkenkamp-Demtröder, Reinert, Sanchez-Carbayo, Segersten, Malmström, Palou, Alvarez-Múgica, Pan, Ulhøi, Borre, Ørntoft, Dyrskjøt: "Multicenter validation of cyclin D1, MCM7, TRIM29, and UBE2C as prognostic protein markers in non-muscle-invasive bladder cancer." in: The American journal of pathology, Vol. 182, Issue 2, pp. 339-49, (2013) (PubMed).

Morikawa, Kawai, Abe, Kume, Homma, Fukayama: "UBE2C is a marker of unfavorable prognosis in bladder cancer after radical cystectomy." in: International journal of clinical and experimental pathology, Vol. 6, Issue 7, pp. 1367-74, (2013) (PubMed).

Guo, Li, Yang, Zhou, Zhang, Zhao: "Oligonucleotide microarray identifies genes differentially expressed during tumorigenesis of DMBA-induced pancreatic cancer in rats." in: PLoS ONE, Vol. 8, Issue 12, pp. e82910, (2013) (PubMed).

Jiang, Wang, Bao, Qian, Wu, Hu, Lu: "A study of UbcH10 expression and its association with recurrence of meningiomas." in: Journal of surgical oncology, Vol. 106, Issue 3, pp. 327-31, (2012) (PubMed).

Chen, Chen, Hu, Jing, Cao, Liu: "Association of clinicopathological features with UbcH10 expression in colorectal cancer." in: Journal of cancer research and clinical oncology, Vol. 136, Issue 3, pp. 419-26, (2010) (PubMed).

Jiang, Huang, Lu, Luo, Hu, Liu, Chen, Han: "Expression of ubiquitin-conjugating enzyme E2C/UbcH10 in astrocytic tumors." in: Brain research, Vol. 1201, pp. 161-6, (2008) (PubMed).

Townsley, Aristarkhov, Beck, Hershko, Ruderman: "Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 6, pp. 2362-7, (1997) (PubMed).

Synonyms and alternative names related to UBE2C

ubiquitin conjugating enzyme E2 C (UBE2C), ubiquitin-conjugating enzyme E2C (NAEGRDRAFT_82946), ubiquitin conjugating enzyme E2 C L homeolog (ube2c.L), ubiquitin-conjugating enzyme E2C (Ube2c), ubiquitin conjugating enzyme E2 C S homeolog (ube2c.S), ubiquitin-conjugating enzyme E2C (ube2c), 1110015A16Rik, D2Ertd695e, dJ447F3.2, im:7137135, LOC458287, UBCH10, zgc:123190

Protein level used designations for UBE2C

  • ubiquitin-conjugating enzyme E2C
  • UBC-X
  • ubiquitin carrier protein C
  • ubiquitin-protein ligase C
  • cyclin-selective ubiquitin carrier protein
  • mitotic-specific ubiquitin-conjugating enzyme
  • ubiquitin-conjugating enzyme E2 C
  • ubcH10
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