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VNN1 Products

(Vanin 1 (VNN1))

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This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq, Feb 2009].

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Featured VNN1 Categories

VNN1 Antibodies

High quality antibodies with extensive validation data.

VNN1 ELISA Kits

Reliable ELISA kits for a wide range of species.

VNN1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended VNN1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7438370
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7435037
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7162595
Quantity 100 μg
Datasheet Datasheet

Recommended VNN1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (10)
  • (1)
Cat. No. ABIN6960435
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (1)
Cat. No. ABIN6960433
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6960434
Quantity 96 tests
Datasheet Datasheet

Recommended VNN1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1325026
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325028
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7320102
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our VNN1 products

Hosohata, Jin, Takai, Iwanaga: "Involvement of Vanin-1 in Ameliorating Effect of Oxidative Renal Tubular Injury in Dahl-Salt Sensitive Rats." in: International journal of molecular sciences, Vol. 20, Issue 18, (2020) (PubMed).

Washino, Hosohata, Jin, Takai, Miyagawa: "Early urinary biomarkers of renal tubular damage by a high-salt intake independent of blood pressure in normotensive rats." in: Clinical and experimental pharmacology & physiology, Vol. 45, Issue 3, pp. 261-268, (2018) (PubMed).

Al Zaabi, Al Salam, Al Suleimani, Manoj, Nemmar, Ali: "Gum Acacia Improves Renal Function and Ameliorates Systemic Inflammation, Oxidative and Nitrosative Stress in Streptozotocin-Induced Diabetes in Rats with Adenine-Induced Chronic Kidney Disease." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 45, Issue 6, pp. 2293-2304, (2018) (PubMed).

Ou, Liu, Li, Zhu, Lin, Han, Duan, Jia, Gui: "Citrate attenuates vascular calcification in chronic renal failure rats." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 125, Issue 5, pp. 452-458, (2017) (PubMed).

Ou, Li, Zhu, Gui, Yao, Ma, Zhu, Fu, Ge, Wang, Jia, Tian, Duan: "Citrate Attenuates Adenine-Induced Chronic Renal Failure in Rats by Modulating the Th17/Treg Cell Balance." in: Inflammation, Vol. 39, Issue 1, pp. 79-86, (2016) (PubMed).

Hosohata, Yoshioka, Tanaka, Ando, Fujimura: "Early urinary biomarkers for renal tubular damage in spontaneously hypertensive rats on a high salt intake." in: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 39, Issue 1, pp. 19-26, (2016) (PubMed).

Hosohata, Washino, Kubo, Natsui, Fujisaki, Kurokawa, Ando, Fujimura, Morita: "Early prediction of cisplatin-induced nephrotoxicity by urinary vanin-1 in patients with urothelial carcinoma." in: Toxicology, Vol. 359-360, pp. 71-5, (2016) (PubMed).

Hong, Wu, Ge, Zhou, Shen, Qiang, Zhang, Chen, Wang, Wang, Hong: "Nanosized titanium dioxide resulted in the activation of TGF-β/Smads/p38MAPK pathway in renal inflammation and fibration of mice." in: Journal of biomedical materials research. Part A, Vol. 104, Issue 6, pp. 1452-61, (2016) (PubMed).

Elsalakawy, Ali, Hegazy, Farweez: "Value of vanin-1 assessment in adult patients with primary immune thrombocytopenia." in: Platelets, Vol. 25, Issue 2, pp. 86-92, (2014) (PubMed).

Ali, Alzaabi, Ramkumar, Al-Lawati, Waly, Beegam, Nemmar, Brand, Schupp: "The effect of activated charcoal on adenine-induced chronic renal failure in rats." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 65, pp. 321-8, (2014) (PubMed).

Synonyms and alternative names related to VNN1

vanin 1 (VNN1), vanin 1 (Vnn1), vanin 1 (vnn1), pantetheinase (LOC100217969), HDLCQ8, hdlcq8, Tiff66, tiff66, V-1, vanin-1, vnn1.1

Protein level used designations for VNN1

  • pantetheinase
  • pantetheine hydrolase
  • vanin-1
  • vannin 1
  • vascular non-inflammatory molecule 1
  • vanin 1
  • TIFF66
  • vanin 1, gene 1
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