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VPREB1 Products

(Pre-B Lymphocyte 1 (VPREB1))

Categories

The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. [provided by RefSeq, Oct 2008].

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Featured VPREB1 Categories

VPREB1 Antibodies

High quality antibodies with extensive validation data.

VPREB1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended VPREB1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS, Neut
Validations
  • (4)
Cat. No. ABIN7193342
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN2118836
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN2119232
Quantity 100 μL
Datasheet Datasheet

Recommended VPREB1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3075392
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415683
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405978
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our VPREB1 products

Shimizu, Mundt, Licence, Melchers, Mårtensson: "VpreB1/VpreB2/lambda 5 triple-deficient mice show impaired B cell development but functional allelic exclusion of the IgH locus." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 12, pp. 6286-93, (2002) (PubMed).

Wang, Stephan, Scheffold, Kunkel, Karasuyama, Radbruch, Cooper: "Differential surrogate light chain expression governs B-cell differentiation." in: Blood, Vol. 99, Issue 7, pp. 2459-67, (2002) (PubMed).

Stephan, Elgavish, Karasuyama, Kubagawa, Cooper: "Analysis of VpreB expression during B lineage differentiation in lambda5-deficient mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 7, pp. 3734-9, (2001) (PubMed).

Mårtensson, Ceredig: "Review article: role of the surrogate light chain and the pre-B-cell receptor in mouse B-cell development." in: Immunology, Vol. 101, Issue 4, pp. 435-41, (2000) (PubMed).

Melchers, ten Boekel, Seidl, Kong, Yamagami, Onishi, Shimizu, Rolink, Andersson: "Repertoire selection by pre-B-cell receptors and B-cell receptors, and genetic control of B-cell development from immature to mature B cells." in: Immunological reviews, Vol. 175, pp. 33-46, (2000) (PubMed).

Ohnishi, Shimizu, Karasuyama, Melchers: "The identification of a nonclassical cadherin expressed during B cell development and its interaction with surrogate light chain." in: The Journal of biological chemistry, Vol. 275, Issue 40, pp. 31134-44, (2000) (PubMed).

Synonyms and alternative names related to VPREB1

V-set pre-B cell surrogate light chain 1 (VPREB1), immunoglobulin iota chain (LOC698810), immunoglobulin iota chain-like (LOC486411), pre-B lymphocyte 1 (VPREB1), V-set pre-B cell surrogate light chain 1 (Vpreb1), pre-B lymphocyte gene 1 (Vpreb1), CD179a, IGI, IGVPB, VPREB, VpreB, Vpreb-1

Protein level used designations for VPREB1

  • pre-B lymphocyte 1
  • pre-B lymphocyte gene 1
  • CD179 antigen-like family member A
  • CD179a
  • immunoglobulin iota chain
  • v(pre)B protein
  • Immunoglobulin lambda Vpreb1 chain
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