VTCN1 Products
(V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
Categories
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
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Featured VTCN1 Categories
VTCN1 Antibodies
High quality antibodies with extensive validation data.
VTCN1 ELISA Kits
Reliable ELISA kits for a wide range of species.
VTCN1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended VTCN1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
- (1)
- (7)
Cat. No.
ABIN671736
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7436759
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, IF, Coat, StM
Validations
- (5)
Cat. No.
ABIN6940936
Quantity
100 μg
Datasheet
Datasheet
Recommended VTCN1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN6574330
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6971108
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6976048
Quantity
96 tests
Datasheet
Datasheet
Recommended VTCN1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7273952
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7273962
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7273961
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our VTCN1 products
: "The prognostic impact of B7-H3 and B7-H4 in head and neck squamous cell carcinoma." in: Journal of cancer research and clinical oncology, (2022) (PubMed).: "Increased Serum Levels of Soluble B7-H4 in Patients with Systemic Lupus Erythematosus." in: Iranian journal of immunology : IJI, Vol. 16, Issue 1, pp. 43-52, (2019) (PubMed).
: "VISTA is an acidic pH-selective ligand for PSGL-1. ..." in: Nature, Vol. 574, Issue 7779, pp. 565-570, (2019) (PubMed).
: "Molecular Pathways: Evaluating the Potential for B7-H4 as an Immunoregulatory Target." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 12, pp. 2934-2941, (2018) (PubMed).
: "Clinical relevance of expression of B7-H1 and B7-H4 in ovarian cancer." in: Oncology letters, Vol. 11, Issue 4, pp. 2815-2819, (2016) (PubMed).
: "Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 4, pp. 1495-506, (2016) (PubMed).
: "Assessment of combined expression of B7-H3 and B7-H4 as prognostic marker in esophageal cancer patients." in: Oncotarget, Vol. 7, Issue 47, pp. 77237-77243, (2016) (PubMed).
: "Expression of costimulatory molecules B7-H1, B7-H4 and Foxp3+ Tregs in gastric cancer and its clinical significance." in: International journal of clinical oncology, Vol. 20, Issue 2, pp. 273-81, (2015) (PubMed).
: "B7-H4 expression by nonhematopoietic cells in the tumor microenvironment promotes antitumor immunity." in: Cancer immunology research, Vol. 3, Issue 2, pp. 184-95, (2015) (PubMed).
: "Impact of neoadjuvant chemotherapy on lymphocytes and co-inhibitory B7-H4 molecule in gastric cancer: low B7-H4 expression associates with favorable prognosis." in: Tumour biology, (2014) (PubMed).
Synonyms and alternative names related to VTCN1
V set domain containing T cell activation inhibitor 1 L homeolog (vtcn1.L), V-set domain containing T cell activation inhibitor 1 (VTCN1), V-set domain containing T-cell activation inhibitor 1 (VTCN1), V set domain containing T cell activation inhibitor 1 (vtcn1), V-set domain containing T cell activation inhibitor 1 (Vtcn1), B7-H4, B7h.5, B7h4, B7H4, B7s1, B7S1, B7x, B7X, BC032925, PRO1291, RGD1311204, VCTN1Protein level used designations for VTCN1
- V-set domain-containing T-cell activation inhibitor 1
- V-set domain containing T cell activation inhibitor 1
- V-set domain containing T-cell activation inhibitor 1
- immune costimulatory protein B7-H4
- t cell costimulatory molecule B7x
- B7 family member, H4
- B7 superfamily member 1
- T cell costimulatory molecule B7x
- T-cell costimulatory molecule B7x
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