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anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) Antibodies

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. Additionally we are shipping AKAP12 Kits (22) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AKAP12 83397 Q9WTQ5
AKAP12 83425 Q5QD51
AKAP12 9590 Q02952
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Top anti-AKAP12 Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue,... Immunofluorescence analysis of HeLa cells, using AKAP12 Antibody. The ... 100 μg Log in to see 2 to 3 Days
$275.00
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged AKAP12 is approximately 0.0... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Cow Sheep Un-conjugated IHC (fro), IP, WB 0.25 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged AKAP12 is approximately 0.0... Western Blot detection against Immunogen (37.62 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30μg whole cell lysate) A:HeLa S3, 5% SDS PAGE antibo... IHC-P Image Immunohistochemical analysis of paraffin-embedded human se... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Mouse Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (fp), IF, WB 100 μL Log in to see 6 to 11 Days
$485.71
Details

AKAP12 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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Human , , , ,
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Top referenced anti-AKAP12 Antibodies

  1. Human Monoclonal AKAP12 Primary Antibody for ELISA, WB - ABIN393479 : Yoshida, Kato, Yokoi, Oguri, Watanabe, Metoki, Yoshida, Satoh, Aoyagi, Nozawa, Yamada: Association of genetic variants with hemorrhagic stroke in Japanese individuals. in International journal of molecular medicine 2010 (PubMed)
    Show all 5 references for ABIN393479

  2. Human Monoclonal AKAP12 Primary Antibody for ELISA, WB - ABIN564142 : Tan, Tan, Lin, Lim, Hew, Chung: Quantitative and temporal proteome analysis of butyrate-treated colorectal cancer cells. in Molecular & cellular proteomics : MCP 2008 (PubMed)
    Show all 2 references for ABIN564142

  3. Cow (Bovine) Polyclonal AKAP12 Primary Antibody for IHC (fro), IP - ABIN264964 : Lin, Tombler, Nelson, Ross, Gelman: A novel src- and ras-suppressed protein kinase C substrate associated with cytoskeletal architecture. in The Journal of biological chemistry 1996 (PubMed)

  4. Human Polyclonal AKAP12 Primary Antibody for IF, IHC - ABIN1533824 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)

More Antibodies against AKAP12 Interaction Partners

Zebrafish A Kinase (PRKA) Anchor Protein 12 (AKAP12) interaction partners

  1. Loss of akap12 function causes severe defects in locomotor activity in zebrafish embryos.

  2. Zebrafish embryos depleted of akap12 (akap12 morphants) exhibited severe hemorrhages.

  3. Gravin is required for the conversion of mesodermal cells from a highly migratory behavior to the medio-laterally intercalative behavior required for body axis extension.

  4. These results provide an important step forward in understanding the mechanism of Gravin function in cell shape regulation and provide valuable insight into how Gravin acts as a cytoskeletal regulator.

Mouse (Murine) A Kinase (PRKA) Anchor Protein 12 (AKAP12) interaction partners

  1. The enrichment of activated Cdc42 (show CDC42 Antibodies) in SSeCKS-null leading edge filopodia correlated with recruitment of the Cdc42 (show CDC42 Antibodies)-specific guanine nucleotide exchange factor (show ARHGEF12 Antibodies), Frabin (show FGD4 Antibodies).

  2. AKAP12 scaffolding protein mediates meningeal reconstruction after central nervous system injury

  3. Results suggest that AKAP12-positive cells in the fibrotic scar may restrict excessive inflammation, demonstrating mechanisms that could underlie the beneficial actions of the fibrotic scar in the new tissue formation stage during the CNS repair process.

  4. We conclude that gravin compartmentalizes a significant pool of PKA that regulates learning-induced beta2-adrenergic receptor (show ADRB2 Antibodies) signaling and ERK (show EPHB2 Antibodies) activation in the hippocampus

  5. Our study implicates a role for SSeCKS in preventing of skin cancer progression possibly through negatively regulating FAK (show PTK2 Antibodies) expression.

  6. controls the localization and activity of cyclin D1 (show CCND1 Antibodies) in parietal epithelial cells and influences proliferative injury in the glomerulus

  7. PKC-mediated remodeling of the actin cytoskeleton is likely regulated by the ability of SSeCKS to control PKC signaling and activity through a direct scaffolding function

  8. Akap12 controls Rb-mediated cell aging and oncogenic progression by directly scaffolding and attenuating PKCalpha (show PKCa Antibodies)/delta.

  9. SERPINB5 (show SERPINB5 Antibodies) and AKAP12 may have a role in increased metastasis in pancreatic ductal adenocarcinoma

  10. SSeCKS has a restricted distribution within the nervous system and that expression of this protein may reflect the specific signaling requirements of a distinct population of nociceptive sensory neurons.

Human A Kinase (PRKA) Anchor Protein 12 (AKAP12) interaction partners

  1. results suggest that the association between the 6q25.1 locus and breast cancer risk may be mediated through single nucleotide polymorphisms that regulate expressions of the AKAP12 gene.

  2. The authors propose that Gravin-mediated recruitment of Aurora A (show AURKA Antibodies) and Plk1 (show PLK1 Antibodies) to the mother (oldest) spindle pole contributes to the fidelity of symmetric cell division.

  3. The SSeCKS, a major Lipopolysaccharide (LPS (show IRF6 Antibodies)) response protein, has been involved in regulating astrocyte activation via production of proinflammatory factor in CNS inflammation.

  4. Elevated expression of AKAP12 is characteristic of paclitaxel-resistant high-grade serous ovarian cancer cells, and a prognostic and predictive marker for poor overall survival in SOC (show UBXN11 Antibodies) patients.

  5. Cigarette smoke-induced changes in AKAP5 (show AKAP5 Antibodies) and AKAP12 in patients with COPD (show ARCN1 Antibodies) may affect efficacy of pharmacotherapy.

  6. The enrichment of activated Cdc42 (show CDC42 Antibodies) in SSeCKS-null leading edge filopodia correlated with recruitment of the Cdc42 (show CDC42 Antibodies)-specific guanine nucleotide exchange factor (show RASGRF1 Antibodies), Frabin (show FGD4 Antibodies).

  7. AKAP12 scaffolding protein mediates meningeal reconstruction after central nervous system injury

  8. PKA compartmentalization via AKAP220 (show AKAP11 Antibodies) and AKAP12 contributes to endothelial barrier regulation.

  9. This study showed that AKAP12,CAMK2D (show CAMK2D Antibodies) and a molecular pathway(cyclic amp (show APRT Antibodies))association to outcome of depressive during citalopram treatment.

  10. AKAP12 variant 2 hypoxic induction shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells

AKAP12 Antigen Profile

Protein Summary

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Gene names and symbols associated with AKAP12

  • A kinase (PRKA) anchor protein (gravin) 12b (akap12b) antibody
  • A kinase (PRKA) anchor protein 12 (AKAP12) antibody
  • A kinase (PRKA) anchor protein 12 (LOC100346982) antibody
  • A kinase (PRKA) anchor protein (gravin) 12 (Akap12) antibody
  • A kinase (PRKA) anchor protein 12 (Akap12) antibody
  • AI317366 antibody
  • AKAP12 antibody
  • AKAP12A antibody
  • AKAP12B antibody
  • AKAP12G antibody
  • AKAP250 antibody
  • cb27 antibody
  • esr1 antibody
  • fb72g12 antibody
  • id:ibd1202 antibody
  • sb:cb27 antibody
  • si:ch73-192g21.1 antibody
  • Srcs5 antibody
  • SSeCKS antibody
  • Tsga12 antibody
  • wu:fb72g12 antibody
  • wu:fc21c03 antibody

Protein level used designations for AKAP12

A kinase (PRKA) anchor protein (gravin) 12 , A-kinase anchor protein 12 , gravin , A kinase (PRKA) anchor protein 12 , A kinase anchor protein 12 , A-kinase anchor protein 12-like , a-kinase anchor protein 12-like , AKAP-12 , gercelin , germ cell lineage protein gercelin , src-suppressed C kinase substrate , testis specific gene A12 , v-src suppressed transcript 5 , SSeCKS, Gravin, AKAP250 , A-kinase anchor protein, 250kDa , AKAP 250 , Src-Suppressed C Kinase Substrate , kinase scaffold protein gravin , myasthenia gravis autoantigen gravin

GENE ID SPECIES
567365 Danio rerio
641446 Macaca mulatta
100396277 Callithrix jacchus
100439715 Pongo abelii
100346982 Oryctolagus cuniculus
100482756 Ailuropoda melanoleuca
100606496 Nomascus leucogenys
83397 Mus musculus
83425 Rattus norvegicus
9590 Homo sapiens
476246 Canis lupus familiaris
513774 Bos taurus
421634 Gallus gallus
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